The effect of increased fibre intake on HbA1c and peripheral immune cells in diabetes

Not Applicable

Completed

• Conditions: Type 2 Diabetes; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12621001149853
• Lead Sponsor: Capital and Coast DHB

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-08-26
• Study Completion: 2023-04-12
• Last Update Posted: 4 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Males and females 18 years - 85 years
Pre-diabetes or type 2 diabetes with HbA1c between 45 mmol/mol and 70 mmol/mol inclusive from a test within the last 3 months. At least 75% of participants will have an HbA1c >50mmol/mol.
A low fibre intake of <18g/day for women or 22g/day for men using the Massey University DFiT fibre screening tool.
Willing to maintain stable diet and exercise patterns throughout the study
Stable medication for lipid lowering and hypertension for 3 months prior to study entry

Exclusion Criteria

Previous bariatric surgery
Pregnancy or breast feeding
Immune altering medications – long-term antibiotics, steroids, immune suppressants
Insulin use
Swallowing difficulties (therefore unable to consume Metamucil)
Unable to consume psyllium soluble fibre for any reason – allergy, physical difficulties

Study & Design

• Study Type: Interventional
• Study Design: Not specified