se of pig collagen graft to increase the thickness of tissue around dental implants that have inflammation around them in order to strengthen the tissue and resolve the inflammatio
Not Applicable
Completed
- Conditions
- Peri-implant mucositisOral Health
- Registration Number
- ISRCTN83600326
- Lead Sponsor
- Geistlich Pharma (Switzerland)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
1. Patients with implant retained mandibular over dentures with at least two fixtures
2. Presence of less than 1mm keratinised mucosa at the implant site
3. Clinical presence of peri-implant mucositis
4. Aged between 50 and 80 years
Exclusion Criteria
1. ASA III and above
2. Smokers
3. Pregnancy
4. Patients on medications recognised to cause Drug Induced Gingival Overgrowth
5. Patients on anti-inflammatory drugs and steroids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Keratinised tissue width is measured using a periodontal probe at baseline and 3 months.
- Secondary Outcome Measures
Name Time Method <br> 1. Pro-inflammatory cytokine levels around the implants collected on Periopaper strips analysed with V-PLEX Proinflammatory Panel 1 (human) Kit at baseline and 3 months<br> 2. Probing depths measured with a periodontal probe at baseline and 3 months<br> 3. Plaque and bleeding scores measured by observation following probing at baseline, 3, 6 and 12 months.<br>