The effect of collagen supplementation on human tendon protein synthesis
Recruiting
- Conditions
- Healthy tendon and injured anterior cruciate ligament protein synthesis10043237
- Registration Number
- NL-OMON53210
- Lead Sponsor
- HAN University of Applied Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Planned for ACL reconstruction with hamstring or quadriceps autograft
Age >=18 and <=40 years.
BMI >=18.5 and <=30 kg/m2
Exclusion Criteria
• Blood donation during the study period or during the last 2 months
• Pregnancy
• Third generation oral contraceptives
• Consumption of >21 alcoholic beverages per week
• Use of any medications known to affect protein metabolism (i.e.
corticosteroids, non-steroidal anti-inflammatories, or prescribed acne
medications).
• Regular use of protein or other nutritional supplements (including vitamins).
• Reported slimming or medically prescribed diet
• Use of antibiotics in the past month
• Current participation in another biomedical research study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Assess the impact of collagen supplementation on healthy tendon protein<br /><br>synthesis in otherwise healthy individuals (18 - 40 y) scheduled for<br /><br>ACL-surgery. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Assess the impact of collagen supplementation on injured ligament and healthy<br /><br>muscle protein synthesis, based on ligament and muscle tissues that also become<br /><br>available during the ACL-surgery.</p><br>