The effect of training status on muscle energy metabolism in young males
- Conditions
- Ageing, Sarcopenia, Mitochondrial Function
- Registration Number
- NL-OMON22088
- Lead Sponsor
- prof. dr. Jaap KeijerWageningen University and ResearchHuman and Animal Physiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
•18-28 year old male
•BMI 18.5-25 kg/m2
Exclusion Criteria
•Health concerns regarding respiratory and pulmonary diseases, such as COPD, (exercise induced) asthma and cardiovascular disease.
•(known symptoms of) Metabolic diseases, such as type I or II diabetes,
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this study is to measure mitochondrial capacity using NIRS in order to verify if NIRS can be used to analyse differences in training status in a normal student population.
- Secondary Outcome Measures
Name Time Method •To measure mitochondrial capacity in gastrocnemius and the wrist flexor muscles to compare which measurement site correlates best to measurements of whole body oxygen consumption.<br><br /><br /><br>•To study the correlation between muscle-recovery to pre-exercise state, expressed as Tc measured using NIRS, and whole body-recovery to pre-exercise state, expressed as EPOC measured using indirect calorimetry.<br><br /><br /><br>•To critically asses the use of the PBMCs as a functional biomarker and assess correlations with whole body and skeletal muscle mitochondrial capacity.<br><br /><br /><br>•To investigate to which extend physical activity questionnaires can be used to reliably estimate VO2max in young and healthy and generally comparatively fit) males <br><br />