ISRCTN84990302
Completed
未知
Cortisol hyper-reactivity to stress - a putative biomarker for major depressive disorder
Cambridgeshire and Peterborough NHS Foundation Trust (UK)0 sites228 target enrollmentMay 12, 2010
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Topic: Mental Health Research Network
- Sponsor
- Cambridgeshire and Peterborough NHS Foundation Trust (UK)
- Enrollment
- 228
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged 16 \- 21 years old
- •2\. Male and female
- •3\. Recruited from Roots study
Exclusion Criteria
- •1\. Take regular steroid medication (oral or inhaled) or take hormonal contraceptives containing oestrogens (combined pill, injection, implant or patch)
- •2\. Hypertension requiring regular treatment
- •3\. Systolic blood pressure above 140 mmHg or resting pulse over 100 mmHg at the start of the study
- •4\. Current respiratory disease, e.g., asthma
- •5\. A personal or family history (parent or sibling) of panic disorder
- •6\. Significant claustrophobia
- •7\. Smoke daily; no smoking on day of assessment
- •8\. Migraine within the last year
- •9\. Current heart disease
- •10\. Females will be excluded if they are or think they might be pregnant, are lactating, or their menstrual cycle has not returned to being regular after pregnancy
Outcomes
Primary Outcomes
Not specified
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