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Clinical Trials/ISRCTN84990302
ISRCTN84990302
Completed
未知

Cortisol hyper-reactivity to stress - a putative biomarker for major depressive disorder

Cambridgeshire and Peterborough NHS Foundation Trust (UK)0 sites228 target enrollmentMay 12, 2010

Overview

Phase
未知
Intervention
Not specified
Conditions
Topic: Mental Health Research Network
Sponsor
Cambridgeshire and Peterborough NHS Foundation Trust (UK)
Enrollment
228
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 12, 2010
End Date
TBD
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Cambridgeshire and Peterborough NHS Foundation Trust (UK)

Eligibility Criteria

Inclusion Criteria

  • 1\. Aged 16 \- 21 years old
  • 2\. Male and female
  • 3\. Recruited from Roots study

Exclusion Criteria

  • 1\. Take regular steroid medication (oral or inhaled) or take hormonal contraceptives containing oestrogens (combined pill, injection, implant or patch)
  • 2\. Hypertension requiring regular treatment
  • 3\. Systolic blood pressure above 140 mmHg or resting pulse over 100 mmHg at the start of the study
  • 4\. Current respiratory disease, e.g., asthma
  • 5\. A personal or family history (parent or sibling) of panic disorder
  • 6\. Significant claustrophobia
  • 7\. Smoke daily; no smoking on day of assessment
  • 8\. Migraine within the last year
  • 9\. Current heart disease
  • 10\. Females will be excluded if they are or think they might be pregnant, are lactating, or their menstrual cycle has not returned to being regular after pregnancy

Outcomes

Primary Outcomes

Not specified

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