The comparison of effectiveness of high leukocyte and low leukocyte PRP in tendinopathy and partial tear of rotator cuff

Phase 3

• Conditions: M75.40; Condition 1: rotator cuff tendinopathy, partial tear of rotator cuff. Condition 2: Shoulder impingement.; Rotator cuff tear or rupture, not specified as traumatic; Impingement syndrome of unspecified shoulder; M75.1

• Registration Number: IRCT20100718004409N12
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Shoulder pain lasted more than 6 weeks
At least 3 positive specific shoulder tests
MRI findings implying tendinopathy or partial tear of rotator cuff

Exclusion Criteria

Shoulder pain that lasted less than six weeks
The presence of sensory or motor disturbances caused by the cervical radiculer pain
Evidence from other pathologies that can lead to shoulder pain. For example, the presence of calcified tendonitis or adhesive capsulitis and ...
History of shoulder surgery in the last 6 months
The presence of inflammatory rhomatologic diseases such as rheumatoid arthritis, fibromyalgia, poly mialia rheumatica and ...
Complete rupture of rotator cuff tendons based on MRI findings
The presence of ligamentous laxity or shoulder instability based on physical examination
History of corticosteroid, analgesic or hyaluronic acid injection in the shoulder joint over the past 3 months
History of exercise therapy and physiotherapy modalities over the past 6 weeks
The history of treatment with PRP in the last 6 months
Use of other therapies during the intervention period
Patients request for discontinuing the treatment
Contraindications for performing MRI or PRP in patients
Any non-rheumatologic inflammatory disease and severe acute infection in patients
Thrombocytopenia in patients

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain amount. Timepoint: Before intervention, 1 ,3 ,6 months after intervention. Method of measurement: Visual Analog Scale.;Function of the patients. Timepoint: Before intervention, 1 ,3 ,6 months after intervention. Method of measurement: WORC & DASH questionnaires.

Secondary Outcome Measures

Name	Time	Method
Shoulder range of motion. Timepoint: Before the intervention, 1,3,6 months after intervention. Method of measurement: Goniometry.;Rotator cuff strength. Timepoint: Before the intervention, 1,3,6 months after intervention. Method of measurement: Muscle Manual Test.