Study to compare the effect of a medicine (lignocaine) given by two ways,first one is by vapour (nebulisation)and second by injection into the blood to reduce the blood pressure and heart rate changes during the procedure of passing the tube into the wind pipe(trachea) tube to wind pipe
Phase 2
- Conditions
- Health Condition 1: null- Age group between 18 and 65years of eithergender belonging to ASAPS 1 undergoing any surgery under general anaesthesia with endotracheal intubation.
- Registration Number
- CTRI/2018/04/013462
- Lead Sponsor
- Kasturba Medical College PG thesis fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Elective surgical procedures under general anaesthesia requiring endotracheal intubation
Age between 18 to 60 years age of either gender
Modified Mallampati class I & II
ASA PS I
Exclusion Criteria
1. Anticipated difficult airway
2. Baseline heart rate < 50 bpm
3. At risk for gastric aspiration
4. BMI > 30 kg/m2
5. Known allergy to lignocaine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method hemodynamic response <br/ ><br>1)Heart rate <br/ ><br>2)Mean arterial pressureTimepoint: 1- Baseline value <br/ ><br>2- Just before laryngoscopy <br/ ><br>3- Immediately after laryngoscopy and intubation <br/ ><br>4- Every minute after laryngoscopy and intubation for the first 5 minutes <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method Duration of laryngoscopyTimepoint: Should not exceed 15 seconds