Comparison of preventive effects of Ketamine ,fentanyl and paracetamol on Hemodynamic parameters and acute postoperative pain after deep vitrectomy
Phase 3
- Conditions
- Most cases of vitrectomy are performed due to retinal detachment for any reason, including diabetes, trauma, etc..
- Registration Number
- IRCT20201213049697N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
all patient candidate for deep vitrectomy surgery
Exclusion Criteria
each surgery that long more than 3 or less than 1 hour
pregnancy
addiction to cigarette ,opium and alcohol
Inability to speak
non iranian nationality
more than 100 kg weight
choronic pain that last more than 6 month
uncontroled systemic diseases such as liver or kidney disease
allergy or anaphylaxy to NSAID ,opium and drug that we use in study
psychosis ,obvious anxiety before surgery and History of taking anti-anxiety medication
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodynamic changes (blood pressure, respiration rate, heart rate, blood oxygen saturation). Timepoint: Before the operation, during the operation (at intervals of 15 minutes, 30 minutes, one hour, two hours), after the operation (at intervals of 15 minutes, 30 minutes, one hour, two hours, 4 hours, 16 hours , 24 hours ). Method of measurement: Mercury sphygmomanometer, clock, pulse oximeter.;Acute pain after surgery. Timepoint: Before the operation, during the operation (at intervals of 15 minutes, 30 minutes, one hour, two hours), after the operation (at intervals of 15 minutes, 30 minutes, one hour, two hours, 4 hours, 16 hours , 24 hours ). Method of measurement: Visual Analogue Scale.
- Secondary Outcome Measures
Name Time Method