Effect of probiotics on patients with NAFLD

Not Applicable

• Conditions: on Alchoholic Fatty Liver Disease.; Fatty (change of) liver, not elsewhere classified

• Registration Number: IRCT2012122911920N1
• Lead Sponsor: Baqiyatallah University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients with NAFLD; the age range was 18 to 65 years old.
Exclusion criteria: patients with NAFLD that used supplemental probiotics of probiotic foods during last 3 monthes; also those used tobacco and alcohol; patients with cardiovascular diseases, chronic liver and kidney diseases, Wilson disease, Hemochromatosis; people with low immune system ability (autoimmune) and pregnant or lactating women.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Malodialdehyde (MDA). Timepoint: Before and after Intervention. Method of measurement: ELISA.;TAC. Timepoint: Before and after Intervention. Method of measurement: ELISA.;Serum Insulin Levels. Timepoint: Before and After Intervention. Method of measurement: ELISA.;IL-6. Timepoint: Before and After Intervention. Method of measurement: ELISA.;Serum Glucose. Timepoint: Before and after Intervention. Method of measurement: Autoanalyzer.;Lipid Profile ( Tg,Total Chol, LDL-C, HDL-C ). Timepoint: Before and After Intervention. Method of measurement: Autoanalyzer.;TNF-a. Timepoint: Before and after Intervention. Method of measurement: ELISA.;OxLDL. Timepoint: Before and after Intervention. Method of measurement: ELISA.;ALT. Timepoint: Before and after Intervention. Method of measurement: autoanalyzer.;AST. Timepoint: Before and after Intervention. Method of measurement: autoanalyzer.