Effect of High-flow Nasal Cannula in High Carbon Dioxide Patients
- Conditions
- Diseases of th respiratory system
- Registration Number
- KCT0003448
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 100
Patients in the emergency room or admitted to the hospital who have non-severe hypercapnia which is defined as partial pressure of arterial carbon dioxide of 43 - 69 mmHg and PH above 7.3 by arterial blood gas.
1. Patients with any sign of imminent respiratory failure requiring intubation and mechanical ventilation
2. Patients with unstable hemodynamics (systolic blood pressure less than 100 mmHg, mean blood pressure less than 60 mmHg, or heart rate faster than 120 beats per minute
3. Patients with shock, intractable arrhythmia, post-CPR status, or ECMO
4. Patients with consciousness disorder which would require intubation (e.g., not responsive, agitated, uncooperative, high risk for aspiration)
5. Patients who had facial surgery, trauma or deformity and airway obstruction that precludes application of nasal cannula.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Partial pressure of carbon dioxide
- Secondary Outcome Measures
Name Time Method umber of patients who were discontinued from HFNC according to the treatment failure criteria and the changes in vital signs and other parameters in ABGA