The Efficacy of Intra-articular Tranexamic acid combined with Epinephrine in Arthroscopic ACL reconstruction: Double-blinded randomized controlled trial
Phase 4
- Conditions
- ACL injuryTranexamic acidACL injury patient
- Registration Number
- TCTR20211124002
- Lead Sponsor
- akornping Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 124
Inclusion Criteria
Patient who underwent primary single-bundle arthroscopic ACL reconstruction using a hamstring autograft with or without meniscal surgeries in Nakornping hospital from 1st June 2021 to 31st May 2023
Exclusion Criteria
Use of other grafts
Revision ACL reconstruction
Concomitant knee cartilage or collateral ligament surgeries
History of knee surgery on the affected knee
Concomitant fracture
Coagulation or bleeding disorders
Preoperative anticoagulation treatment
History of tranexamic acid or epinephrine allergy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Drain output volume 24 hours postoperative ml
- Secondary Outcome Measures
Name Time Method Different of hemoglobin level pre- and postoperative at 24 hours g/dL,Range of motion pre- and postoperative at 2, 6, 12 weeks Degrees,Mid patellar circumference pre- and postoperative at 2, 6, 12 weeks cm,Lysholm score pre- and postoperative at 2, 6, 12 weeks Points,International Knee Documentation Committee score pre- and postoperative at 2, 6, 12 weeks Points,Hemarthrosis grading postoperative day 3 Grade,Calf circumference postoperative day 3 cm