SEVOFLURANE Vs PROPOFOL FOR ANAESTHESIA MAINTENANCE IN PAEDIATRIC MRI

Not Applicable

Conditions: Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes

Registration Number: CTRI/2020/12/029961

Lead Sponsor: Seth GS Medical College and KEM Hospital Mumbai

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

American Society of Anaesthesiology (ASA) status I and II children between 1-12years of age, without any evidence of an anticipated difficult airway and severe systemic disease.

Exclusion Criteria

1. Severe cardiovascular, pulmonary, endocrine, renal and hepatic disease

2. Severe airway or craniofacial abnormality

3. History of propofol intolerance, family history of malignant hyperthermia and mitochondrial disease,

4. Fat metabolism disorder

5. Imaging for acute trauma

6. History suggestive of recent respiratory tract infection

7. Inadequate fasting

8. Children receiving intravenous anesthetic agents or sedative agents other than propofol

9. Children with tracheostomy in-situ

10. Children requiring mechanical ventilation, supplemental oxygen and inotropic support

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To estimate the efficacy of sevoflurane in comparison to propofol in terms of interruptions in paediatric MRI during maintenance of anaesthesiaTimepoint: On completion of the MRI scan

Secondary Outcome Measures

Name	Time	Method
To compare the following parameters between the two study groups: <br/ ><br>(a) Time to awakening <br/ ><br>(b) Time spent in PACU until fulfillment of PACU discharge criteria <br/ ><br>(c) Incidence of respiratory complications during the MRI scan <br/ ><br>(d) Incidence of cardiovascular complications during the MRI scan <br/ ><br>(e) Incidence of emergence delirium <br/ ><br>(g) Incidence of post-procedure vomitingTimepoint: All the above mentioned secondary outcomes will be assessed on completion of MRI scan