The Effect of Protein Ingestion on the Recovery of Skeletal Muscle Function Following Eccentric Exercise.

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Dietary Supplement: Post exercise protein-polyphenol supplement; Dietary Supplement: Post exercise placebo supplement; Dietary Supplement: Pre bed protein-polyphenol supplement; Dietary Supplement: Pre bed placebo supplement

• Registration Number: NCT02980900
• Lead Sponsor: University of Exeter

Brief Summary

The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-11-30
• Study First Submitted QC: 2016-11-30
• Study First Posted: 2016-12-02
• Study Start: 2017-01-01
• Primary Completion: 2018-08-01
• Study Completion: 2018-08-01
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-11
• Last Update Posted: 2018-10-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Men and women who are generally healthy and recreationally active

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Exclusion Criteria

• Active cardiovascular disease or hypertension
• Diagnosed metabolic impairment
• Use of nutritional supplements
• Use of anti-inflammatory medications
• Habitual dietary protein intake of <0.8g/kg/day
• Musculoskeletal disorders

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Post exercise supplement	Post exercise protein-polyphenol supplement	Post exercise protein-polyphenol supplement Pre bed placebo supplement
Post exercise + pre bed supplement	Pre bed protein-polyphenol supplement	Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement
Placebo supplement	Post exercise placebo supplement	Post exercise placebo supplement Pre bed placebo supplement
Placebo supplement	Pre bed placebo supplement	Post exercise placebo supplement Pre bed placebo supplement
Pre bed supplement	Post exercise placebo supplement	Post exercise placebo supplement Pre bed protein-polyphenol supplement
Pre bed supplement	Pre bed protein-polyphenol supplement	Post exercise placebo supplement Pre bed protein-polyphenol supplement
Post exercise supplement	Pre bed placebo supplement	Post exercise protein-polyphenol supplement Pre bed placebo supplement
Post exercise + pre bed supplement	Post exercise protein-polyphenol supplement	Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement

Primary Outcome Measures

Name	Time	Method
Isokinetic force production of the knee extensor muscles	14 days

Secondary Outcome Measures

Name	Time	Method
Thigh volume	14 days
Perceived muscle soreness	14 days
Isometric force production of the knee extensor muscles	14 days
Muscle protein synthesis	14 days

Trial Locations

Locations (1)

Sport and Health Sciences; 🇬🇧 Exeter, Devon, United Kingdom