The Effect of Protein Ingestion on the Recovery of Skeletal Muscle Function Following Eccentric Exercise.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Exeter
- Enrollment
- 36
- Locations
- 2
- Primary Endpoint
- Isokinetic force production of the knee extensor muscles
Study Overview
Brief Summary
The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Men and women who are generally healthy and recreationally active
Exclusion Criteria
- •Active cardiovascular disease or hypertension
- •Diagnosed metabolic impairment
- •Use of nutritional supplements
- •Use of anti-inflammatory medications
- •Habitual dietary protein intake of <0.8g/kg/day
- •Musculoskeletal disorders
Arms & Interventions
Placebo supplement
Post exercise placebo supplement Pre bed placebo supplement
Intervention: Post exercise placebo supplement (Dietary Supplement)
Placebo supplement
Post exercise placebo supplement Pre bed placebo supplement
Intervention: Pre bed placebo supplement (Dietary Supplement)
Post exercise supplement
Post exercise protein-polyphenol supplement Pre bed placebo supplement
Intervention: Post exercise protein-polyphenol supplement (Dietary Supplement)
Post exercise supplement
Post exercise protein-polyphenol supplement Pre bed placebo supplement
Intervention: Pre bed placebo supplement (Dietary Supplement)
Pre bed supplement
Post exercise placebo supplement Pre bed protein-polyphenol supplement
Intervention: Post exercise placebo supplement (Dietary Supplement)
Pre bed supplement
Post exercise placebo supplement Pre bed protein-polyphenol supplement
Intervention: Pre bed protein-polyphenol supplement (Dietary Supplement)
Post exercise + pre bed supplement
Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement
Intervention: Post exercise protein-polyphenol supplement (Dietary Supplement)
Post exercise + pre bed supplement
Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement
Intervention: Pre bed protein-polyphenol supplement (Dietary Supplement)
Outcomes
Primary Outcomes
Isokinetic force production of the knee extensor muscles
Time Frame: 14 days
Secondary Outcomes
- Thigh volume(14 days)
- Perceived muscle soreness(14 days)
- Isometric force production of the knee extensor muscles(14 days)
- Muscle protein synthesis(14 days)