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临床试验/NCT04561895
NCT04561895已完成不适用

Genetic Variations in Adipokine to Improve Risk Prediction for NAFLD and Its Progression to NASH in Egyptian Patients

Cairo University1 个研究点 分布在 1 个国家目标入组 224 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
224
试验地点
1
主要终点
investigate adipokine dna polymorphism

研究概览

简要总结

Due to the limited data concerning Egyptian population. authors aimed to investigate the differentadipokine gene polymorphism related to non alcoholic fatty liver disease incidence, prognosis and progression to steotosis and also to find different related factors including obesitu, diabetes and liver enzymes level

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Egyptian patients confirmed NAFLD diagnosis diabetic

排除标准

  • Pregnancy and lactation, history of alcohol abuse (as defined by an average daily consumption of alcohol > 30 g/day in men and > 20 g/day women), cirrhosis, autoimmune hepatitis and other causes of liver disease (viral hepatitis, hemochromatosis, Wilson's disease), drug induced hepatitis, chronic enteropathies, Chronic kidney disease

结局指标

主要结局

investigate adipokine dna polymorphism

时间窗: 1 months

to investigate adipokine gene polymorphism associated with prognosis of NAFLD patients

correlations

时间窗: 1 month

to correlate between gene polymorphism and glycated hemoglobin, liver enzyme and obesity

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dalia K. Zaafar

lecturer of pharmacology

Cairo University

研究点 (1)

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