Management of Miller’s class I/II gingival recession with titanium platelet-rich fibrin membrane: Case series.

Not yet recruiting

• Conditions: Chronic periodontitis,

• Registration Number: CTRI/2022/10/046294
• Lead Sponsor: DR KARTIK RADADIYA

Brief Summary

Gingival Recession is definedas exposure of the root surface due to apical migration of the gingival marginbeyond the cementoenamel junction.Treatment with Titanium-PRF autogenous  graft  allows  for thicker fibrin meshwork, continued integrity,tightly woven and thicker fibrin scaffold, more polymerized fibrin formation, longerresorption time (30 days), increased duration of released growth factor, excellentbiocompatibility, better hemocompability and platelet activation.

**AIM:**

To clinically evaluate and compare the outcome of Titanium-Plateletrich fibrin (T-PRF) membrane versus Connective Tissue Graft (CTG) using theconventional tunnel technique, in treatment of Miller’sclass I/II gingivalrecession sites, over a period of   6months.

**METHODOLOGY**

Presentstudy is a randomized controlled clinical trial with a Sample size of 20 subjects,having Miller’s class I/II recession sites. Following the selection ofrecession sites, patients will be randomly divided into two groups: GROUP 1 (TESTGROUP): - 10 sites with Miller’s class I/II gingival recessions to be treated with T-PRF. GROUP 2(CONTROL GROUP): - 10 sites with Miller’s class I/II gingival recession to be treatedwith CTG. Clinical Parameters to be assessed at Baseline (pre surgical phase), 1Month, 3 Months and 6 Months after therapy are: Recession depth ,Recession width ,Probing pocket depth ,Clinical attachment level, Keratinized tissue width. The visualanalog scale (VAS) will be measured during procedure and at 14 days aftertherapy. Wound Healing Index will be measured at 14 days and 1month aftertherapy. The statistical analysis will be done using paired ‘t’test and unpaired‘t’test.

**PROPOSEDCONCLUSION**:-

It is expectedthat the use of T-PRF will be equally effective to CTG in treatment  of Miller’s class I/II gingival recession.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-07-10
• Study Start: 2022-12-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• 1.Teeth with Miller’s class I or II gingival recession.
• 2.Vital teeth with no restoration or decay.
• 3.Teeth with no mobility and no occlusal trauma.
• 4.Patients who can follow the instructions and maintain a good oral hygiene.

Exclusion Criteria

• 1.Pregnant and lactating women.
• 2.Patients having fixed orthodontic or removable prosthesis on surgical sites.
• 3.Patients with smoking habits.
• 4.The presence of periodontal pockets exceeding 5 mm in the teeth undergoing treatment.
• 5.Any systemic disease likely to influence coagulation.
• 6.Patients on anti-coagulant medicines.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected that the use of T-PRF will be equally effective to CTG in gaining recession depth and recession width .	Baseline,14 day,1 month ,3 months , 6 months

Secondary Outcome Measures

Name	Time	Method
With T-PRF improvement in clinical parameters such as RD, RW, PPD, CAL and KTW.	BASELINE, 14 DAYS, 1 MONTH, 3 MONTHS, 6 MONTHS

Trial Locations

Locations (1)

Pacific Dental College and Hospital; 🇮🇳 Udaipur, RAJASTHAN, India

Pacific Dental College and Hospital

🇮🇳Udaipur, RAJASTHAN, India

DR KARTIK RADADIYA

Principal investigator

9106591119

kartikradadiya36@gmail.com