Vitamin D and Thyroid Function in patients with Anxiety and Depressive Disorder
- Conditions
- Health Condition 1: F411- Generalized anxiety disorderHealth Condition 2: F33- Major depressive disorder, recurrentHealth Condition 3: F32- Major depressive disorder, singleepisode
- Registration Number
- CTRI/2024/05/066905
- Lead Sponsor
- niversity college of medical sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients with age between 18-60 years.
2. Patient must meet criteria for: Either
Primary diagnosis of Generalized Anxiety Disorder according to ICD-10 (The ICD-10 Classification of Mental and Behavioural Disorders) [Annexure 1]
OR
Primary diagnosis of Depressive episode- Mild, moderate or severe, or Recurrent Depressive Disorder according to ICD-10 (The ICD-10 Classification of Mental and Behavioural Disorders) [Annexure 2]
3. Patients should be able to read Hindi/English
1. Lifetime ICD-10 diagnosis of schizophrenia, schizoaffective or bipolar disorders.
2. Patients previously diagnosed with and undergoing treatment for any significant or
chronic medical illness which alters vitamin D or thyroid hormone levels (renal disease,
thyroid dysfunction, hepatic disease)
3. Patients consuming vitamin D supplements in the last 6 months.
4. Pregnant or lactating women.
5. Patients with substance dependence of alcohol and illicit substances (except nicotine).
6. Patients not consenting for participation in the study or for giving blood sample.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum 25-hydroxyvitamin D levels in patients with Generalized Anxiety Disorder and <br/ ><br>Depressive DisorderTimepoint: 1 week
- Secondary Outcome Measures
Name Time Method 1. To evaluate thyroid function tests in patients of Generalized Anxiety Disorder and Depressive Disorder. <br/ ><br>2. To study the correlation of serum levels of 25-hydroxyvitamin D and thyroid function tests with severity of anxiety, if any. <br/ ><br>3. To study the correlation of serum levels of 25-hydroxyvitamin D and thyroid function tests with severity of depression, if anyTimepoint: 1 week