Cognitive decline according to Amyloid Uptake in patients with post-Stroke cognitivE impairment

The Catholic University of Korea, Eunpyeong St. Mary's Hospital0 个研究点目标入组 196 人开始时间: 待定最近更新: 2020年6月15日

适应症

试验速览

暂无简介。

•1) patients who were diagnosed as mild cognitive impairment within 3 months from acute cerebral infarct
•2) aged 60-80
•3) cognitive impairments were newly developed or aggravated after cerebral infarct

•1) patient who was diagnosed as dementia before the cerebral infarct
•2) other neurological, psychiatric, or medical disease that cause cognitive impairment
•3) patient taking a cholinesterase inhibitor within 3 months from baseline
•4) strategic infarct or large territory infarct involving cortical areas
•5) modified Rankin Scale (mRS) >3
•6) patients with aphasia
•7) blindness, deafness, or severe language impairment that might be impossible for study evaluations
•8) severe liver disease or kidney disease that needs dialysis
•9) malignancy that was not completely resolved
•10) schizophremia or bipolar disorders (DSM-IV Axis I psychiatric disease)
•11) mental retardation
•12) history of encephalitis
•13) head trauma history that caused loss of consciousness>1 hour
•14) history of traumatic intracranial hemorrhage, brain tumor, or subarachnoid hemorrhage
•15) abnormality in thyroid function tests
•16) vitamin B12 or folate deficiency
•17) neurosyphilis
•18) history of metabolic encephalopathy

发起方

The Catholic University of Korea, Eunpyeong St. Mary's Hospital