Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

Not Applicable

Completed

• Conditions: Intensive Care Unit Syndrome; Muscle Weakness
• Interventions: Procedure: Early ambulation

• Registration Number: NCT02919085
• Lead Sponsor: Universidade Federal de Pernambuco

Brief Summary

To analyze changes on respiratory muscle strength, peripheral and functional capacity of critically ill patients with clinical and surgical etiology, breathing spontaneously and bedridden, within 48 hours of admission to the intensive care unit (ICU) and if there are correlations among these variables. This is an observational study. Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP) and peripheral muscle strength, by the Medical Research Council score (MRC) and hand grip test and functional capacity through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s) in the period between 24h and 48h of hospitalization in the adult ICU. For descriptive purposes, the sample will be stratified according to clinical and surgical characteristics. Correlations will be determined using the Pearson test, with significance level of p \<0.05.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-09-23
• Study First Submitted QC: 2016-09-27
• Study First Posted: 2016-09-29
• Study Start: 2016-12
• Primary Completion: 2017-10
• Study Completion: 2017-12
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-22
• Last Update Posted: 2021-08-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Breathing spontaneously
• Length of stay in ICU greater than 24 hours
• Adherence to study

Exclusion Criteria

• Patients with poor prognosis or palliation;
• Preexisting neuromuscular diseases;
• Immobility or restriction to bed prior to admission;
• Nonunions and amputations;
• Osteomioarticular, cognitive or neurological impairment;
• Non-cooperation;
• Specific contraindications to the application of evaluation methods;
• Hemodynamic or respiratory instability within 48 hours of ICU admission preventing evaluation muscle strength and functional capacity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Mobilization	Early ambulation	-

Primary Outcome Measures

Name	Time	Method
Functional capacity	48 hours	The functional capacity will be assessed through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s).
Respiratory muscle strength	48 hours	Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP).
Peripheral muscle strength	48 hours	The peripheral muscle strength will be assessed through the Medical Research Council score (MRC) and hand grip test.

Trial Locations

Locations (1)

Real Hospital Português de Beneficência; 🇧🇷 Recife, Pernambuco, Brazil