Electrogustometric study of trigemino-gustatory interactions in humans

Not Applicable

• Conditions: oral diseaes and physiology

• Registration Number: PACTR201602001452260
• Lead Sponsor: Cheikh Anta Diop University and Hospitalo-University Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 313

Inclusion Criteria

age between 18 and 70, no significant health issues (i.e. absence of cardiovascular disease, systemic disease, chronic immunosuppression, hemophilia or asthma) and no current medication intake, non-smokers, restorative or Endodontic Treatment required on mandibular premolars or molars, no more than two missing teeth within the hemimandibula, no more than eight posterior teeth absent in total, no history of chronic orofacial pain for at least three weeks before the start of the study, no oral mucosal abnormality (ulceration, lichen planus etc.), no tongue piercing and agreement to sign an informed consent.

Exclusion Criteria

Patients that do not fulfill the inclusion criteria, patients responding positively when EGM delivered no electrical current before anesthetic injection, patients presenting a lack of sensitivity in all loci before anesthetic injection or patients in which anesthesia was not effective after 30 minutes following injection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main result of this randomized controlled clinical trial is a statistically significant increase in EGMt ipsilateral to the side (p<0.05) of the anaesthetized of the inferior alveolar nerve (IAN) (trigeminal) at dorsal and posterior sites of the tongue following anesthesia.

Secondary Outcome Measures

Name	Time	Method
Secondary results were: a statistically significant increases in the EGMt ipsilateral to the side of the anesthetized mandibular nerve (MdN) in all the ipsilateral sites of the tongue following anesthesia and a lack of variation in the EGMt following maxillary anesthesia in any site of the tongue surface.