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The Efficacy of Probiotics together with Sequential regimen in Helicobacter pylori(Hp) eradication.

Phase 3
Conditions
Helicobacter pylori eradication.
Registration Number
IRCT20180715040480N1
Lead Sponsor
Zanjan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
100
Inclusion Criteria

All Patient have Higher than 18 years age with Dyspepsia & Hp Positive

Exclusion Criteria

Recently had Hp eradication therapy
Hypersensitivity to Amoxicillin, Clarithromycin or Metronidazol
History of Uncontrolled Cardiac, Renal, Hepatic or Glandular diseases
History of Gastrointestinal Surgery
History of Malignancies
Pregnancy or Lactation

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Response rates in Helicobacter pylori eradication therapy. Timepoint: 4 weeks after the end of treatment. Method of measurement: Stool Antigen of Helicobacter pylori.
Secondary Outcome Measures
NameTimeMethod
Vomiting. Timepoint: During 10 days of treatment. Method of measurement: Side effects questionarie for Helicobacter pylori treatment.;Abdominal pain. Timepoint: During 10 days of treatment. Method of measurement: Side effects questionarie for Helicobacter pylori treatment.;Diarrhea. Timepoint: During 10 days of treatment. Method of measurement: Side effects questionarie for Helicobacter pylori treatment.;Taste disturbance. Timepoint: During 10 days of treatment. Method of measurement: Side effects questionarie for Helicobacter pylori treatment.;Nausea. Timepoint: During 10 days of treatment. Method of measurement: Side effects questionarie for Helicobacter pylori treatment.
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