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Effect of IV dexmedetomidine on intraoperative stress reaction during trans-sphenoidal surgery: A randomized trial

Not Applicable
Completed
Conditions
Diseases of the nervous system
Registration Number
KCT0003366
Lead Sponsor
Samsung Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
46
Inclusion Criteria

Age=19 or >19 years old
Patients undergoing pituitary tumor resection
American Society of Anesthesiologist physical status I,II, III

Exclusion Criteria

American Society of Anesthesiologist physical status IV, V
Age under 18 years old
Age over 70 years old
Pregnency
unstable coronary artery disease, congestive heart failure, cardiomyopathy
Cerebral disease
Patient refusal
Allergy to study drug
Psychyatric disease
Complete AV block, mild conduction delay, severe sinus bradycardia
severe liver disease, severe renal insufficiency

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Stress hormone concentrations
Secondary Outcome Measures
NameTimeMethod
pain score;intraoperative blood pressure and heart rate;Cumulative opioid consumption at 24 hours postoperatively;perioperative sedation;Length of PACU stay
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