Effects of dairy protein on muscle protein synthesis at rest and after exercise

Not Applicable

Completed

• Conditions: Muscle loss; Musculoskeletal - Normal musculoskeletal and cartilage development and function

• Registration Number: ACTRN12615001375549
• Lead Sponsor: David Cameron-Smith

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-12-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

BMI (18-30kg/m2)
Sedentary to moderately active

Exclusion Criteria

1.Diabetes or symptoms of metabolic syndrome or current pharmaceutical therapy

2.Other medical conditions impacting on digestion, including diseases of the gastrointestinal tract, allergy to dairy protein and history (or medical management) of mental illness

4.Smoking

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Muscle protein synthesis in rested and post exercise states. A primed consistant infusion of 13C6 Phenylalanine will be combined with arterialized blood samples and muscle biopsies to calculate the fractional synthetic rate.[0-90 minutes after beverage consumption, 90 to 210 min after beverage consumption ]

Secondary Outcome Measures

Name	Time	Method
Plasma amino acid concentrations [0, 15, 30, 45, 60,75,90,120,150,180 and 210 min after beverage consumption ];Isometric knee extension strength [prior to beverage consumption ];Body composition measured by DXA [Prior to beverage consumption];Thigh muscle size measured by pqCT [prior to beverage consumption ]