Improving the Pregnancy Rate With Endometrial Sampling Before Intrauterine Insemination
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- The rate of clinical pregnancy
研究概览
简要总结
Endometrial sampling improves the pregnancy rates in superovulation-IUI cycles
详细描述
Endometrial sampling is performed using the standard technique in the outpatient department. Similarly, superovulation with gonadotrophins will be performed according to our standard practice.Endometrial sampling will be done in the follicular phase not later than day 10 of the cycle. Endometrial sampling will be performed using Pipelle sampling catheter. The Pipelle is inserted gently through the cervical canal into the uterine cavity and advanced slowly till just resistance felt by the operator. Then, the piston is withdrawn to create negative suction and gentle movement of Pipelle up and down in the uterine cavity is performed while it is against the uterine wall. The Pipelle catheter is withdrawn gently and any obtained specimen will be sent for histopathological examination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All women undergoing superovulation with gonadotrophins and intrauterine insemination.
- •All women with cervical factor, mild male factor and/or unexplained infertility.
- •At least one patent Fallopian tube.
排除标准
- •Bilateral tubal disease
- •Severe male factor infertility
- •Intrauterine pathology (submucosal fibroid, endometrial polyp, adhesions)
- •Women with positive cervical culture and/or acute vaginal infection
结局指标
主要结局
The rate of clinical pregnancy
时间窗: 24 months
次要结局
未报告次要终点
研究者
Mohammed Agdi
Consultant Reproductive Endocrinology and Infertility
McGill University Health Centre/Research Institute of the McGill University Health Centre