EFFECT OF N-ACETYL CYSTEINE THERAPY ON ENZYME AFFECTING SPERM ACTIVITY IN SEMEN IN MALE INFERTILITY : A PILOT STUDY
Not Applicable
- Conditions
- Health Condition 1: N46- Male infertility
- Registration Number
- CTRI/2023/02/049522
- Lead Sponsor
- niversity college of medical sciences and guru teg Bahadur hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Males with 2 abnormal semen analysis reports at 2-3 weeks interval,of oligozoospermia and/or asthenozoospermia and not on any hormonal or antioxidant therapy
Exclusion Criteria
1.Cases of azoospermia confirmed on 3 occasions. 2.Men with erectile or ejaculatory dysfunction or with inability to provide semen sample. 3.History of any febrile illness or surgery in the past 3 months. 4. Males with chronic medical disorder like diabetes,hypertension and tuberculosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of seminal PAF-AH activity before and after NAC therapyTimepoint: 3 months
- Secondary Outcome Measures
Name Time Method 1)Association of PAF-AH activity with semen parameters before and after NAC therapy. 2)Comparison of semen parameters before and after NAC therapy. 3) To assess the side effects of NAC,if any.Timepoint: 3 months