Role of CMR-FT in Assessment of HCM and Athlete's Heart.

Active, not recruiting

• Conditions: Hypertrophic Cardiomyopathies; Athlete Heart

• Registration Number: NCT06859827
• Lead Sponsor: Sohag University

Brief Summary

Using cardiac MRI feature tracking to asses myocardial motion differences in athlete's heart and discovered hypertrophic cardiomyopathy patients to increase diagnostic accuracy of hypertrophic cardiomyopathy.

Detailed Description

Cardiac MRI is the gold standard for assessing cardiac function without significant limitations of anatomical restrictions. CMR-FT helps in assessment of myocardial deformation on routinely obtained by steady state free precision (SSFP) cine images. CMR-FT is used in cardiac research and became common in clinical practice. It has been used in assessment of wide spectrum of cardiac diseases and provides for comprehensive and reliable assessments of heart function.

Study Timeline

• Study Start: 2024-12-15
• Status Verified: 2025-02
• Study First Submitted: 2025-02-28
• Study First Submitted QC: 2025-02-28
• Last Update Submitted: 2025-02-28
• Study First Posted: 2025-03-05
• Last Update Posted: 2025-03-05
• Primary Completion: 2025-11-15
• Study Completion: 2025-12-15

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients suspected to be hypertrophic cardiomyopathy by echocardiography..
• Athletes and heavy workers,, healthy volunteers also included.

Exclusion Criteria

• Patients with absolute or relative contraindications to magnetic resonance imaging (e.g intra-ocular metallic foreign body, claustrophobia, etc) or contra-indication to MRI contrast medium.
• Clinical morbidities with absolute contraindication to anesthesia during the examination in un-cooperative patients where sedation is required.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Use of cardiac MRI feature tracking in detection of myocardial deformation abnormalities and diagnostic confirmation and detection of hypertrophic cardiomyopathy.	6months to 12 months	The main goal of the study is evaluating the role of Cardiac magnetic resonance feature tracking analysis in detection of myocardial deformation abnormalities in cases of hypertrophic cardio myopathy and compare it with physiological hypertrophy in athletes.; Identification of strain patterns in hypertrophic cardiomyopathy.

Trial Locations

Locations (1)

Sohag University hospital; 🇪🇬 Sohag, Egypt