Explore the mechanism of Qigong Pill regulating AdipoR/AMPK pathway to improve oocyte quality in patients with phlegm-dampness PCOS based on network pharmacological analysis
- Conditions
- PCOS
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
(1) married women aged between 25 and 40 years;
(2) Diagnosed polycystie ovarian syndrome;
(3) indications in accordance with IVF;
(4) the conditions of reproductive endocrine and vaginal color ultrasound are in accordance with the standard of downregulation;
(5) knowingly and agree to participate in the treatment of this study and receive follow-up.
(1) the uterus does not have pregnancy function or severe somatic diseases cannot bear pregnancy;
(2) those who use hormone drugs in the past 3 months;
(3) suffering from serious cardiovascular and cerebrovascular diseases, such as hypertension, coronary heart disease and other liver and kidney diseases, mental disorders; Patients with acute infection of genitourinary system, sexually transmitted diseases and blood diseases;
(4) patients with genetic diseases that are unfertile under the Maternal and Child Health Care Law and are currently unable to undergo preimplantation genetic diagnosis;
(5) diseases with similar clinical and endocrine signs caused by other causes, such as ovarian or adrenal tumors, adrenal cortical hyperplasia, etc.;
(6) those who are exposed to teratogenic radiation, poisons or drugs and are in the active stage;
(7) people with serious bad habits such as drug abuse.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AdipoR1;Adipor2;ACC;APN;p-ACC;the rate of high quality embryo;AMPK;p-ampk;CPT;the rate of high quality oocyte;
- Secondary Outcome Measures
Name Time Method