DNA of Oral Cytobrush in Three Means Conservation
Early Phase 1
Completed
- Conditions
- Healthy
- Interventions
- Procedure: samples collected by buccal cytobrush
- Registration Number
- NCT01038934
- Lead Sponsor
- UPECLIN HC FM Botucatu Unesp
- Brief Summary
The aim of this study is to analyze genomic DNA of buccal cytobrush stored in three means conservation.
- Detailed Description
Blood samples are an excellent source of large amounts of genomic DNA. However, alternative sources are often needed in epidemiological studies because of difficulties in obtaining blood samples.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
- healthy young
Exclusion Criteria
- none
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description buccal cytobrhsh samples collected by buccal cytobrush healthy young
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does buccal cytobrush DNA conservation compare to blood-derived DNA in terms of genomic integrity and mutation detection accuracy?
What are the optimal storage conditions for preserving buccal cytobrush genomic DNA in large-scale epidemiological studies?
Which molecular biomarkers in buccal cell DNA correlate with long-term stability in ethanol-based, RNAlater, and dry storage methods?
What adverse events are associated with buccal cytobrush sample collection in healthy populations, and how are they managed?
How do DNA extraction protocols from oral cytobrush samples impact downstream epigenetic analysis compared to traditional blood sampling?
Trial Locations
- Locations (1)
School of Dentistry, Sao Paulo State University, Unesp, Araçatuba/SP
🇧🇷Araçatuba, São Paulo, Brazil