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Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.

Not Applicable
Conditions
Analgesia
Interventions
Registration Number
NCT02190760
Lead Sponsor
Hillel Yaffe Medical Center
Brief Summary

The addition of dexamethasone (DxaM) to local anesthetic may significantly prolong the duration of a block. The aim of this study is to determine whether this a systemic or local effect.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
90
Inclusion Criteria
  • Pre-surgical patients for arthroscopic or open shoulder surgery
Exclusion Criteria
  • Skin infection near block site
  • Allergy to local anesthetics
  • Peripheral neuropathy
  • Proven opioid dependency
  • Coagulopathy
  • Dementia

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Group II (ISB-S)DexamethasoneInterscalene block with systemically injection of dexamethasone 0.1 mg/kg.
Group I (ISB-P)DexamethasoneInterscalene block with perineural injection of dexamethasone 0.1 mg/kg
Group III - ISB-CBupivacaineInterscalene block without adjuvant.
Group I (ISB-P)BupivacaineInterscalene block with perineural injection of dexamethasone 0.1 mg/kg
Group II (ISB-S)BupivacaineInterscalene block with systemically injection of dexamethasone 0.1 mg/kg.
Primary Outcome Measures
NameTimeMethod
Efficacy DxaM PerineuralOne day

Duration of motor and sensory block.

Secondary Outcome Measures
NameTimeMethod
Efficacy of Systemic DxaMOne day

Duration of motor and sensory block

Trial Locations

Locations (1)

Hillel Yaffe Medical Center

🇮🇱

Hadera, Israel

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