Monitoring cerebral oxygen saturation using near infrared spectroscopy to assess experimentally induced pain: a sequence-randomised, sham-controlled study in volunteers.
Not Applicable
- Conditions
- painhealthy controls
- Registration Number
- DRKS00011575
- Lead Sponsor
- Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
1) voluntariness, 2) healthy, 3) right handed, 4) German knowledge, 5) 18-45 years, 6) written infomred consent
Exclusion Criteria
1) missing declaration of consent, 2) left handed, 3) psychiatric disorder, 4) neurological disorder, 5) disorders like diabetes, polyneuropathy, 6) exposure to medications for analgesia/ hormones, antidepressants, 7) chronic pain
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decrease of cererbal oxygen saturation atfer pain stimulus (each stimulus (UPS, EPS, NPS or PS) was set at ‘0s’, pre-base 1: prior to UPS at ‘-300 to 0s’, pre-base 2 prior EPS, NPS or PS at ‘-180 to -30s’. Warning was given verbally 30s before the stimuli (‘-30 to 0s’). After each stimulus the observational period was divided into different time intervals of about 30s. Post-base ‘150 to 300s’.
- Secondary Outcome Measures
Name Time Method pain intensity on NRS (numerical rating scale; 0 = no pain, 10 = most intense pain imaginable) after expected and an unexpected painful electrical stimuli