Red Cell Life Span (RBC) in Chronic Kidney Disease (CKD)

Not Applicable

Recruiting

• Conditions: Chronic Kidney Disease; Red blood cell life span; Renal and Urogenital - Kidney disease; Blood - Anaemia

• Registration Number: ACTRN12610000145000
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

Patients of at least 18 years of age and on dialysis at least for 2 months haemodialysis (HD) and peritoneal dialysis (PD) will be invited to participate in this study, stable subjects with moderate CKD (stage III, defined as a glomerular filtration rate (GFR) (30-59 ml/min), subjects with diabetes mellitus with normal renal function and healthy controls

Exclusion Criteria

HD and PD patients not on erythropoietin and/or iron supplement therapy. Haemoglobin concentrations not within the recommended target range (Hb: 110-130 g/l). Evidence of recent blood loss and or recent blood transfusion. Intercurrent inflammatory illness or drugs which may influence bone marrow function. Solid organ maligancy. Unstable glycaemic control. Pregnancy. Women of child bearing potential will be advised to practise ab acceptable form of contraception for the duration of the study.

Study & Design

• Study Type: Observational
• Study Design: Not specified