Study of ketamine gargle for relieving sore throat after surgeries under general anaesthesia

Phase 3

• Conditions: Health Condition 1: O- Medical and SurgicalHealth Condition 2: K318- Other specified diseases of stomach and duodenum

• Registration Number: CTRI/2021/03/032075
• Lead Sponsor: Department of Anaesthesia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

The study will be conducted on patients of either gender , between 18-65 years of age belonging to American College of Anaesthesiologists ( ASA ) physical status I & II undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubation

Exclusion Criteria

1.] Patients with difficult airway

2.) Patients with a history of pre - operative sore throat , oral surgeries, asthma, diabetes.

3.) Patients with known allergies to study drug and rescue drugs.

4.) Patients consuming non - steroidal anti - inflammatory drugs or topical steroids within 24 hrs prior to surgery

5. ) Duration of surgery less than 1 hr and more than 4 hours.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the incidence and severity of post - operative sore throat in patients receiving pre operative gargle with 50 mg of ketamine ( 1 ml ) in 29 ml normal saline undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubationTimepoint: Patient followed up for post operative sore throat at 0,2,4,24 hrs after extubation.

Secondary Outcome Measures

Name	Time	Method
To evaluate the incidence and severity of cough and hoarseness of voice in patients receiving pre operative gargle with 50 mg of ketamine ( 1 ml ) in 29 ml normal saline undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubationTimepoint: Patient followed up for cough and hoarseness of voice at 0,2,4,24 hrs after extubation.