Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation in Genito-urinary Paediatric Surgeries
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Emergence Agitation
研究概览
简要总结
The aim of this randomized double-blinded study is to determine whether transition to propofol for 3 min at the end of sevoflurane anaesthesia reduces the incidence of EA in children undergoing genito-urinary paediatric surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 3 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children Aged 3 - 8 years
- •ASA (I - II)
- •Genito-urinary Surgeries: hernia, varicocele, etc.
排除标准
- •Patients or parental refusal
- •Allergy to Propofol or egg products; or a family history of malignant hyperthermia
- •Operating time more than 60 minutes
- •Performance of any other procedure under the same anaesthetic
- •Presence of co-morbidities or congenital anomalies
- •mental disease, neurologic disease, treatment with sedatives, full stomach, or indication for rapid sequence induction.
研究组 & 干预措施
Propofol
propofol 1 mg/kg IV bolus will be given to the patient with a further 2 mg/kg administered manually over the next 3 min prior to the patient leaving the OR
干预措施: Propofol (Drug)
Control
Normal saline will be administered IV over the next 3 min prior to the patient leaving the OR
干预措施: Normal saline (Drug)
结局指标
主要结局
Emergence Agitation
时间窗: 30 min after emergence
The incidence of EA according to the Paediatric Emergence Anaesthesia Delirium (PAED) scale (defined as a score \>12 at any time in the 30 min after emergence )
次要结局
未报告次要终点
研究者
Mostafa Samy Abbas
Lecturer
Assiut University