Effects of meal-sequences on postprandial glucose levels, incretin secretion and gastric emptying: Evaluation in individuals with type 2 diabetes and healthy control.
- Conditions
- Type 2 diabetes
- Registration Number
- JPRN-UMIN000017434
- Lead Sponsor
- Kansai Electric Power Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 24
Not provided
Following individuals are excluded from the study 1)Indivisuals with any adjustments of any drugs during the study period 2)Individuals with moderate or severe renal impairment 3)Individuals on peritoneal dialysis or hemodialysis 4)Individuals with severe hepatic dysfunction 5)Individuals with shock, heart failure, myocardial infarct, pulmonary embolism, sever pulmonary dysfunction, hypoxemia 6)Individuals with excessive alcohol intake 7)Individuals with dehydration, and dehydration-causing severe GI symptoms including diarrhea and vomit 8)Individuals with severe ketosis, or coma. 9)Individuals with severe infection, in the perioperative period or with serious injury 10)Individuals with Hb <13.0 mg/dL (male) and Hb <12.5 mg/dL (female) 11)Individuals allergic to mackerels 12)Individuals with a history of GI operation 13) Individuals pregnant or possibly pregnant 14) Individuals found ineligible as a study patient according to the discretion of the investigator or sub-investigators
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glucose levels, their area under the curve, theri glucose levels, and their standard deviations before and after ingestion of steamed rice.
- Secondary Outcome Measures
Name Time Method 1) levels of insulin, glucagon, GLP-1, GIP and their area under the curve before and after ingestion of steamed rice. 2) time required for 50% ofsteamed rice to exit the stomach (t1/2).