Effect of synbiotics on intestinal environment in healthy subjects - Effect of synbiotics on intestinal environment

Ezaki Glico Co., Ltd.0 个研究点目标入组 40 人开始时间: 2020年10月1日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方: Ezaki Glico Co., Ltd.
入组人数: 40

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

niFrac distance analysis results showed a significant change in the gut microbiome composition of synbiotics group in comparison with that of placebo group. During the intervention period in synbiotics group, there was an increase in the abundance ratio of genus Bifidobacterium and Anaerostipes and a decrease in genus Clostridium. The quantitative PCR results showed that the total number of fecal Bifidobacterium significantly increased in only synbiotics group during the intervention period.

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 65years-old（—）
性别: All

入选标准

未提供

排除标准

•1.Subjects who regularly use intestinal and constipation drugs (including strong laxatives) 2.Subjects who are heavy drinkers or alcoholics. 3.Subjects who consume following foods (daily or during ingestion period): food containing lactic acid bacteria and bifidobacteria (fermented milk, beverages, supplement etc.,), prebiotics and oligosaccharides, food containing a large amount of dietary fiber (beverages, supplements etc.,) 4.Subjects who have a disease that requires emergency treatment, or have serious complications 5.Subjects who have a medical history of digestive diseases or surgeries affecting digestion and absorption 6.Subjects with food allergy 7.Subjects who are pregnant or plan to become pregnant , or breast-feeding during the study 8.Subjects who are participating in other clinical trials that intake/apply any foods or drugs.

研究者

发起方

Ezaki Glico Co., Ltd.

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已完成

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