Influence of early goal-directed therapy using arterial waveform cardiac output measurement in high-risk surgery

Completed

• Conditions: high-risk surgery; 10017998

• Registration Number: NL-OMON44010
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 542

Inclusion Criteria

Included will be patients undergoing the following elective operations, irrespective of their their ASA classification:
- esophagectomy
- pancreaticoduodenectomy
- open abdominal aorta aneurysm (AAA) repair
- major abdominal resections for soft tissue malignancy, in which post-operative observation in the ICU or PACU is necessary
In addition, patients with ASA physical status III or IV undergoing the following operations are included, if post-operative observation in the ICU of PACU is necessary:
- gastrectomy
- colorectal resections for carcinoma
- other extended upper or lower abdominal surgery

Exclusion Criteria

Exclusion criteria are:
- age < 18 years
- cardiac arrhythmias
- emergency surgery
- contraindication for passive leg raising in the entire postoperative period

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is the number of major complications in the first 30 days<br /><br>after the operation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secundary outcome parameters are other complications, length of hospital and<br /><br>ICU/PACU stay, the total amount of fluid and inotropics administrated, and<br /><br>vital functions during surgery and in the OR and ICU/PACU. </p><br>