Vancomycin

Generic Name
Vancomycin
Brand Names
Firvanq, Vancocin
Drug Type
Small Molecule
Chemical Formula
C66H75Cl2N9O24
CAS Number
1404-90-6
Unique Ingredient Identifier
6Q205EH1VU
Background

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
...

Indication

Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associ...

Associated Conditions
Clostridium Difficile Associated Diarrhea (CDAD), Enterocolitis caused by Staphylococcus aureus, Infection caused by staphylococci, Severe Staphylococcal infection
Associated Therapies
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AbioKin - Antibiotic Kinetics

First Posted Date
2015-11-20
Last Posted Date
2021-01-19
Lead Sponsor
Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva
Target Recruit Count
1500
Registration Number
NCT02609646
Locations
🇮🇹

Ospedale S. Giovanni di Dio ASL 10, Servizio Anestesia e Rianimazione, Firenze, FI, Italy

🇮🇹

Ospedale San Giovanni di Dio, Orbetello, Grosseto, Italy

🇮🇹

Ospedale A. Manzoni, U.O. Anestesia e Rianimazione 1, Lecco, Lombardia, Italy

and more 8 locations

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-2

First Posted Date
2015-11-18
Last Posted Date
2018-08-07
Lead Sponsor
Motif Bio
Target Recruit Count
613
Registration Number
NCT02607618
Locations
🇺🇸

St. Mary Medical Center ER, Long Beach, California, United States

🇺🇸

California, Long Beach, California, United States

🇺🇸

Georgia, Columbus, Georgia, United States

and more 16 locations

Effect and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis Patients

First Posted Date
2015-11-16
Last Posted Date
2015-11-16
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
30
Registration Number
NCT02605213
Locations
🇮🇷

Imam khomeini Hospital Complex, Tehran, Iran, Islamic Republic of

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-1

First Posted Date
2015-11-09
Last Posted Date
2018-06-19
Lead Sponsor
Motif Bio
Target Recruit Count
600
Registration Number
NCT02600611
Locations
🇺🇸

Nebraska, Lincoln, Nebraska, United States

🇺🇸

Florida, Miami, Florida, United States

🇺🇸

Washington, Seattle, Washington, United States

and more 14 locations

Intracameral Antibiotic Safety Study

First Posted Date
2015-10-29
Last Posted Date
2022-04-27
Lead Sponsor
Panhandle Eye Group, LLP
Target Recruit Count
500
Registration Number
NCT02590523
Locations
🇺🇸

Rush Eye, Amarillo, Texas, United States

Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA

First Posted Date
2015-10-21
Last Posted Date
2016-11-01
Lead Sponsor
Wayne State University
Target Recruit Count
174
Registration Number
NCT02582203
Locations
🇺🇸

St. John Hospital and Medical Center, Detroit, Michigan, United States

🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

🇺🇸

Detroit Medical Center, Detroit, Michigan, United States

FMT for Moderate to Severe CDI: A Randomised Study With Concurrent Stool Microbiota Assessment

First Posted Date
2015-10-07
Last Posted Date
2023-02-08
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
30
Registration Number
NCT02570477
Locations
🇭🇰

Prince of Wales Hospital, Hong Kong, Hong Kong

Intestinal Lavage for the Treatment of Severe C. Difficile Infections

First Posted Date
2015-06-09
Last Posted Date
2018-08-13
Lead Sponsor
Lawson Health Research Institute
Target Recruit Count
20
Registration Number
NCT02466698
Locations
🇨🇦

London Health Sciences Centre, London, Ontario, Canada

A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis

First Posted Date
2015-06-08
Last Posted Date
2020-07-17
Lead Sponsor
University of Minnesota
Target Recruit Count
8
Registration Number
NCT02464020
Locations
🇺🇸

University of Minnesota Medical Center, Minneapolis, Minnesota, United States

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