Levetiracetam
- Generic Name
- Levetiracetam
- Brand Names
- Elepsia, Keppra, Matever, Roweepra, Spritam, Levetiracetam Accord, Levetiracetam Teva, Levetiracetam Actavis, Levetiracetam ratiopharm, Levetiracetam Sun, Levetiracetam Actavis Group, Levetiracetam Hospira
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14N2O2
- CAS Number
- 102767-28-2
- Unique Ingredient Identifier
- 44YRR34555
- Background
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). Levetiracetam possesses a wide therapeutic index and little-to-no potential t...
- Indication
Levetiracetam is indicated as an adjunctive therapy in the treatment of partial onset seizures in epileptic patients who are one month of age and older. Additionally, it is indicated as an adjunct in the treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy who are 12 years of age and older, and in primary generalized tonic-clonic seiz...
- Associated Conditions
- Epilepsies, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Myoclonic seizures
- Associated Therapies
- -
Precision Medicine in the Treatment of Epilepsy
- Conditions
- Interventions
- First Posted Date
- 2022-07-11
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Gitte Moos Knudsen
- Target Recruit Count
- 550
- Registration Number
- NCT05450822
- Locations
- 🇩🇰
Neurobiology Research Unit, Rigshospitalet, Copenhagen, Denmark
Study on the Population Pharmacokinetics of Levetiracetam in Epileptic Patients With Diabetic Kidney Disease
- Conditions
- First Posted Date
- 2022-04-15
- Last Posted Date
- 2022-04-15
- Lead Sponsor
- The Second Hospital of Shandong University
- Target Recruit Count
- 50
- Registration Number
- NCT05330390
- Locations
- 🇨🇳
Second Hospital of Shandong University, Jinan, Shandong, China
Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children
- First Posted Date
- 2021-06-15
- Last Posted Date
- 2022-09-21
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 144
- Registration Number
- NCT04926844
- Locations
- 🇪🇬
Department of Pediatrics - Sohag University Hospital, Sohag, Egypt
rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease
- Conditions
- Interventions
- First Posted Date
- 2021-04-06
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Myrtelle Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT04833907
- Locations
- 🇺🇸
Dayton Children's Hospital, Dayton, Ohio, United States
Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas
- First Posted Date
- 2021-02-18
- Last Posted Date
- 2021-04-30
- Lead Sponsor
- Université de Sherbrooke
- Target Recruit Count
- 56
- Registration Number
- NCT04759196
- Locations
- 🇨🇦
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease
- Conditions
- Interventions
- First Posted Date
- 2020-11-25
- Last Posted Date
- 2022-11-04
- Lead Sponsor
- The University of Queensland
- Target Recruit Count
- 28
- Registration Number
- NCT04643327
- Locations
- 🇦🇺
University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia
Changing Agendas on Sleep, Treatment and Learning in Epilepsy
- Conditions
- Interventions
- First Posted Date
- 2020-11-02
- Last Posted Date
- 2020-11-02
- Lead Sponsor
- King's College London
- Target Recruit Count
- 5
- Registration Number
- NCT04610879
- Locations
- 🇬🇧
King's College Hospital NHS Foundation Trust, London, United Kingdom
🇬🇧Whiston Hospital, Whiston, United Kingdom
🇬🇧Tameside Hospital, Manchester, United Kingdom
Pharmacological Management of Seizures Post Traumatic Brain Injury
- Conditions
- Interventions
- First Posted Date
- 2020-10-05
- Last Posted Date
- 2020-11-03
- Target Recruit Count
- 1649
- Registration Number
- NCT04573803
Modified Atkins Diet Versus Levetiracetam for Refractory Childhood Epilepsy
- Conditions
- Interventions
- First Posted Date
- 2019-11-21
- Last Posted Date
- 2019-11-21
- Lead Sponsor
- Lady Hardinge Medical College
- Target Recruit Count
- 90
- Registration Number
- NCT04172311
- Locations
- 🇮🇳
Lady Hardinge Medical College, New Delhi, Delhi, India
Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE)
- First Posted Date
- 2019-07-02
- Last Posted Date
- 2019-07-02
- Lead Sponsor
- Walter Reed National Military Medical Center
- Target Recruit Count
- 65
- Registration Number
- NCT04004702
- Locations
- 🇺🇸
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Drug Development Updates
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