Salmeterol

Generic Name
Salmeterol
Brand Names
Advair, Airduo, Airduo Respiclick, Serevent, Serevent Diskus, Wixela
Drug Type
Small Molecule
Chemical Formula
C25H37NO4
CAS Number
89365-50-4
Unique Ingredient Identifier
2I4BC502BT
Background

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure i...

Indication

用于哮喘(包括夜间哮喘和运动性哮喘)、喘息性支气管炎和可逆性气道阻塞。

Associated Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Exercise-Induced Bronchospasm
Associated Therapies
-

Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease

First Posted Date
2011-07-12
Last Posted Date
2013-08-07
Lead Sponsor
Dartmouth-Hitchcock Medical Center
Target Recruit Count
20
Registration Number
NCT01391559
Locations
🇺🇸

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States

Fluticasone and Salmeterol in Allergic Rhinitis

First Posted Date
2011-07-06
Last Posted Date
2019-10-16
Lead Sponsor
University of Dundee
Target Recruit Count
23
Registration Number
NCT01388595
Locations
🇬🇧

Asthma and Allergy Research Group, University of Dundee, Dundee, United Kingdom

Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography

First Posted Date
2011-05-27
Last Posted Date
2012-07-20
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
20
Registration Number
NCT01361984
Locations
🇺🇸

UCLA, Los Angeles, California, United States

Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI

First Posted Date
2011-05-19
Last Posted Date
2015-10-23
Lead Sponsor
James J. Peters Veterans Affairs Medical Center
Target Recruit Count
40
Registration Number
NCT01355991
Locations
🇺🇸

Kessler Institute for Rehabilitation, West Orange, New Jersey, United States

🇺🇸

James J. Peters VA Medical Center, Bronx, New York, United States

A 4-week Dose-Ranging, Dose-Interval, Efficacy, Safety and Tolerability Study of GSK961081 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2011-03-21
Last Posted Date
2016-12-01
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
437
Registration Number
NCT01319019
Locations
🇺🇦

GSK Investigational Site, Vinnytsia, Ukraine

Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-02-07
Last Posted Date
2018-03-30
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
1070
Registration Number
NCT01290874
Locations
🇺🇸

G.A. Carmichael F.H.C., Canton, Mississippi, United States

🇺🇸

Edward Waters College Medical Center (Mayo), Jacksonville, Florida, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

and more 10 locations

Effect of Salmeterol on Fluid Clearance From Alveolar-Capillary Membrane in COPD Patients

First Posted Date
2011-01-06
Last Posted Date
2011-01-06
Lead Sponsor
University of Milan
Target Recruit Count
20
Registration Number
NCT01271556
Locations
🇮🇹

Respiratory Medicine Section, Dipartimento Toraco-Polmonare e Cardiocircolatorio, Università degli Studi di Milano, San Paolo Hospital, Milan, Italy

Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway

First Posted Date
2010-11-01
Last Posted Date
2016-06-30
Lead Sponsor
University of Miami
Target Recruit Count
14
Registration Number
NCT01231230

Effects of Inhaled Corticosteroids on Sputum Bacterial Load in COPD

First Posted Date
2010-10-04
Last Posted Date
2016-04-08
Lead Sponsor
Università degli Studi di Ferrara
Target Recruit Count
60
Registration Number
NCT01213693
Locations
🇮🇹

Research Centre on Asthma and COPD - Department of Clinical and Experimental Medicine - Section of Respiratory Disease - University of Ferrara, Ferrara, Italy

Efficacy and Safety of Different Doses of Indacaterol

First Posted Date
2010-03-02
Last Posted Date
2011-08-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
511
Registration Number
NCT01079130
Locations
🇺🇸

Novartis Investigative site, North Charleston, South Carolina, United States

🇺🇸

Novartis Investigator Site, Seattle, Washington, United States

🇺🇸

Novartis Investigative Site, Charleston, South Carolina, United States

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