Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis
- Conditions
- Interventions
- First Posted Date
- 2024-03-08
- Last Posted Date
- 2024-05-22
- Lead Sponsor
- Sadat City University
- Target Recruit Count
- 46
- Registration Number
- NCT06302049
- Locations
- 🇪🇬
National Liver Institute, Shibīn Al Kawm, Egypt
The ESG Integrity Study: Effect of Proton Pump Inhibitors on the Structural Integrity of Endoscopic Sleeve Gastroplasty
- First Posted Date
- 2024-02-28
- Last Posted Date
- 2024-02-28
- Target Recruit Count
- 40
- Registration Number
- NCT06283381
- Locations
- 🇮🇹
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant
- First Posted Date
- 2024-02-23
- Last Posted Date
- 2024-06-03
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 12
- Registration Number
- NCT06275841
- Locations
- 🇺🇸
Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut, United States
Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection
- First Posted Date
- 2024-01-22
- Last Posted Date
- 2024-02-09
- Lead Sponsor
- National Institute of Public Health, Slovenia
- Target Recruit Count
- 2000
- Registration Number
- NCT06216639
- Locations
- 🇸🇮
Community Healthcare Center dr. Adolf Drolc Maribor (HCM), Maribor, Slovenia
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participant
- Conditions
- Interventions
- First Posted Date
- 2024-01-19
- Last Posted Date
- 2024-03-21
- Lead Sponsor
- Incyte Corporation
- Target Recruit Count
- 84
- Registration Number
- NCT06213818
- Locations
- 🇦🇺
Nucleus Network Pty Ltd, Melbourne, Victoria, Australia
A Study in Healthy People to Compare Two Different Tablets of BI 685509 and to Test How Food and Esomeprazole Influence the Amount of BI 685509 in the Blood
- Conditions
- Interventions
- First Posted Date
- 2024-01-05
- Last Posted Date
- 2024-03-20
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 16
- Registration Number
- NCT06193811
- Locations
- 🇩🇪
Humanpharmakologisches Zentrum Biberach, Biberach, Germany
A Study Comparing Different Formulations of LY3410738 in Healthy Adult Participants
- First Posted Date
- 2023-12-26
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 60
- Registration Number
- NCT06181084
- Locations
- 🇺🇸
Labcorp Clinical Research, Daytona Beach, Florida, United States
Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
- First Posted Date
- 2023-12-13
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Yongquan Shi
- Target Recruit Count
- 688
- Registration Number
- NCT06168084
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shanxi, China
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
- Conditions
- Interventions
- First Posted Date
- 2023-12-08
- Last Posted Date
- 2024-08-28
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 242
- Registration Number
- NCT06162949
- Locations
- 🇪🇬
Faculty of Medicine, Alexandria, Egypt
Doxycycline for Helicobacter Pylori Rescue Treatment
- Conditions
- Interventions
- First Posted Date
- 2023-05-25
- Last Posted Date
- 2023-09-25
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 368
- Registration Number
- NCT05874570
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Drug Development Updates
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