Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
A Study of Vonoprazan in Adults With Helicobacter Pylori
- Conditions
- Interventions
- First Posted Date
- 2021-02-15
- Last Posted Date
- 2023-08-31
- Lead Sponsor
- Takeda
- Target Recruit Count
- 44
- Registration Number
- NCT04753437
- Locations
- 🇨🇳
West China Hospital, Sichuan University, Phase I Unit, Chengdu, Sichuan, China
The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole
- Conditions
- Interventions
- First Posted Date
- 2021-01-22
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Showa Inan General Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT04720781
- Locations
- 🇯🇵
Showa Inan General hospital, Komagane, Nagano, Japan
Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
- First Posted Date
- 2020-12-22
- Last Posted Date
- 2023-01-31
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 658
- Registration Number
- NCT04678492
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
Effectiveness of Rifabutin for Treatment of Helicobacter Pylori
- First Posted Date
- 2020-12-03
- Last Posted Date
- 2021-03-10
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 300
- Registration Number
- NCT04652284
Effectiveness of Minocycline-Containing Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
- First Posted Date
- 2020-09-22
- Last Posted Date
- 2022-01-13
- Target Recruit Count
- 339
- Registration Number
- NCT04558502
Rescue Therapy for Helicobacter Pylori Eradication
- Conditions
- Interventions
- First Posted Date
- 2020-08-28
- Last Posted Date
- 2023-01-26
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 368
- Registration Number
- NCT04531059
- Locations
- 🇨🇳
Shanghai East Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China
🇨🇳Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
🇨🇳The Second Affiliated Hospital of Zhejiang University school of Medicine, Hangzhou, Zhejiang, China
A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)
- Conditions
- Interventions
- First Posted Date
- 2020-07-13
- Last Posted Date
- 2022-05-10
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 24
- Registration Number
- NCT04468815
- Locations
- 🇺🇸
ICON (LPRA) - Salt Lake, Salt Lake City, Utah, United States
Intravenous Triple Therapy in the Treatment of Helicobacter Pylori Infection and Related Complications Caused by Active Peptic Ulcer Disease
- Conditions
- Interventions
- First Posted Date
- 2020-06-16
- Last Posted Date
- 2020-08-27
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 60
- Registration Number
- NCT04432233
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.
- Conditions
- Interventions
- First Posted Date
- 2020-04-01
- Last Posted Date
- 2020-04-03
- Lead Sponsor
- Kaohsiung Veterans General Hospital.
- Target Recruit Count
- 218
- Registration Number
- NCT04329000
Study to Evaluate the Efficacy and Safety of Tegoprazan in ERD Patients With Nighttime Heartburn and Sleep Disturbance
- First Posted Date
- 2020-03-17
- Last Posted Date
- 2022-02-25
- Lead Sponsor
- HK inno.N Corporation
- Target Recruit Count
- 46
- Registration Number
- NCT04309916
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.