Atazanavir

Generic Name
Atazanavir
Brand Names
Evotaz, Reyataz, Atazanavir Krka, Atazanavir Viatris (previously Atazanavir Mylan)
Drug Type
Small Molecule
Chemical Formula
C38H52N6O7
CAS Number
198904-31-3
Unique Ingredient Identifier
QZU4H47A3S
Background

Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the pa...

Indication

Atazanavir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 3 months of age and older weighing at least 5kg. Atazanavir is also indicated in combination with cobicistat and other antiretrovirals for the treatment of HIV-1 infection in adults and pediatric patients weighing at l...

Associated Conditions
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Associated Therapies
-

Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2012-05-21
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1125
Registration Number
NCT00013520
Locations
🇺🇸

The Ponce de Leon Ctr. CRS, Atlanta, Georgia, United States

🇺🇸

Northwestern University CRS, Chicago, Illinois, United States

🇺🇸

St. Louis ConnectCare, Infectious Diseases Clinic, St. Louis, Missouri, United States

and more 57 locations

Study of a New Protease Inhibitor, BMS-232632, in Combination With Other Anti-HIV Drugs

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2011-05-04
Lead Sponsor
Bristol-Myers Squibb
Registration Number
NCT00002240
Locations
🇺🇸

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

🇺🇸

Albany Med College, Albany, New York, United States

🇺🇸

Clinsites / Sorra Research Ctr, Birmingham, Alabama, United States

and more 14 locations

Safety and Effectiveness of a Three-Drug Combination Treatment for Recently Infected or Converted HIV Patients

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2021-11-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
55
Registration Number
NCT00007202
Locations
🇺🇸

AIDS Research Consortium of Atlanta, Inc. (ARCA) AIEDRP CRS, Atlanta, Georgia, United States

🇺🇸

Feinberg School of Medicine, HIV/ACTU AIEDRP CRS, Chicago, Illinois, United States

🇺🇸

Rush Univ. Med. Ctr., Dept. of Infectious Disease AIEDRP CRS, Chicago, Illinois, United States

and more 2 locations

A Comparison of BMS-232632 With Efavirenz, Each in Combination With Zidovudine-Lamivudine

Phase 3
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2011-05-04
Lead Sponsor
Bristol-Myers Squibb
Registration Number
NCT00013897
Locations
🇺🇸

Associates in Research, Fort Myers, Florida, United States

🇺🇸

The CORE Ctr, Chicago, Illinois, United States

🇺🇸

Ohio State Univ Hosp, Columbus, Ohio, United States

and more 96 locations

Safety and Effectiveness of a New Protease Inhibitor, BMS-232632, in HIV-Positive Patients Who Have Received Previous Treatment

Phase 2
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2011-05-04
Lead Sponsor
Bristol-Myers Squibb
Registration Number
NCT00004584
Locations
🇺🇸

HIV Clinical Research, Fort Lauderdale, Florida, United States

🇺🇸

Infectious Disease Specialists of Atlanta, Decatur, Georgia, United States

🇺🇸

Albany Med College, Albany, New York, United States

and more 35 locations
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