Nifedipine
- Generic Name
- Nifedipine
- Brand Names
- Adalat, Afeditab CR, Nifediac, Nifedical, Procardia
- Drug Type
- Small Molecule
- Chemical Formula
- C17H18N2O6
- CAS Number
- 21829-25-4
- Unique Ingredient Identifier
- I9ZF7L6G2L
- Background
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and lo...
- Indication
Nifedipine capsules are indicated to treat vasospastic angina and chronic stable angina. Extended release tablets are indicated to treat vasospastic angina, chronic stable angina, and hypertension.
- Associated Conditions
- Achalasia, Chronic Stable Angina Pectoris, Fissure;Anal, Hypertension, Hypertensive Emergency, Premature Labour, Proctalgia, Pulmonary Edemas, Pulmonary Hypertension (PH), Raynaud's Phenomenon, Ureteral Calculus, Vasospastic Angina
- Associated Therapies
- -
Effectiveness of Valsartan/Amlodipine (EXforge®) and Nifedipine treAtment coMparison in Treating Chinese Hypertensive Patients
- First Posted Date
- 2010-07-22
- Last Posted Date
- 2012-06-01
- Lead Sponsor
- Novartis
- Target Recruit Count
- 564
- Registration Number
- NCT01167153
- Locations
- 🇨🇳
Novartis Pharmaceuticals, Beijing, China
Sitaxsentan in Proteinuric Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2009-01-06
- Last Posted Date
- 2009-01-06
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 27
- Registration Number
- NCT00817037
- Locations
- 🇬🇧
Clinical Research Centre, Western General Hospital, Edinburgh, Scotland, United Kingdom
Tocolysis for Preterm Labor
- Conditions
- Interventions
- First Posted Date
- 2008-12-18
- Last Posted Date
- 2013-04-04
- Lead Sponsor
- University of Mississippi Medical Center
- Target Recruit Count
- 301
- Registration Number
- NCT00811057
- Locations
- 🇺🇸
The Winfred L. Wiser Hospital for Women and Infants at the University of Mississippi Medical Center, Jackson, Mississippi, United States
Effects Of Sitaxsentan On Proteinuria, 24-Hour Blood Pressure, And Arterial Stiffness In Chronic Kidney Disease Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-12-18
- Last Posted Date
- 2023-07-06
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 27
- Registration Number
- NCT00810732
- Locations
- 🇬🇧
Clinical Research Centre and Pharmacology Unit, Edinburgh, Scotland, United Kingdom
🇬🇧the University of Edinburgh, Western General Hospital, Department of Medical Sciences, Edinburgh, Scotland, United Kingdom
Endothelin Receptor Antagonism in Proteinuric Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2008-07-25
- Last Posted Date
- 2008-07-25
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 22
- Registration Number
- NCT00722215
- Locations
- 🇬🇧
Clinical Research Centre, Western General Hospital, Edinburgh, Scotland, United Kingdom
Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
- Conditions
- Interventions
- First Posted Date
- 2008-07-11
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- United States Naval Medical Center, San Diego
- Target Recruit Count
- 240
- Registration Number
- NCT00713739
- Locations
- 🇺🇸
Naval Medical Center San Diego, San Diego, California, United States
Oral Nifedipine to Treat Iron Overload
- Conditions
- First Posted Date
- 2008-07-10
- Last Posted Date
- 2017-07-02
- Target Recruit Count
- 6
- Registration Number
- NCT00712738
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Tocolytic Therapy in Conservative Management of Symptomatic Placenta Previa
- First Posted Date
- 2008-02-21
- Last Posted Date
- 2014-07-10
- Lead Sponsor
- University Hospital, Rouen
- Target Recruit Count
- 109
- Registration Number
- NCT00620724
- Locations
- 🇫🇷
University Hospital Rouen, Rouen, France
Nifedipine Compared to Atosiban for Treating Preterm Labor
- First Posted Date
- 2008-01-24
- Last Posted Date
- 2012-03-13
- Lead Sponsor
- Raed Salim
- Target Recruit Count
- 145
- Registration Number
- NCT00599898
- Locations
- 🇮🇱
HaEmek Medical Center, Afula, Israel
Drug Discrimination in Methadone-Maintained Humans Study 1
- Conditions
- Interventions
- First Posted Date
- 2008-01-15
- Last Posted Date
- 2011-03-11
- Lead Sponsor
- University of Arkansas
- Target Recruit Count
- 40
- Registration Number
- NCT00593463
- Locations
- 🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Drug Development Updates
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