Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

Effect of Opioids in Neuropathic Pain in Postherpetic Patients

Phase 3
Conditions
Neuralgia, Postherpetic
First Posted Date
2010-04-12
Last Posted Date
2010-04-12
Lead Sponsor
Medical University of Vienna
Target Recruit Count
30
Registration Number
NCT01102101
Locations
🇦🇹

Wilhelminenspital der Stadt WIen, Vienna, Austria

🇦🇹

General Hospital Vienna, Medical University of Vienna, Vienna, Austria

Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion

Not Applicable
Completed
Conditions
Short Duration Analgesia
Skull Pin Insertion
Interventions
Drug: Remifentanil
First Posted Date
2010-01-26
Last Posted Date
2010-01-26
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
72
Registration Number
NCT01056224
Locations
🇨🇦

Toronto Western Hospital, Toronto, Ontario, Canada

The Effect Site Concentration of Remifentanil for Conscious Sedation During Awake Nasotracheal Fiberoptic Intubation

First Posted Date
2010-01-20
Last Posted Date
2011-05-13
Lead Sponsor
Yonsei University
Target Recruit Count
19
Registration Number
NCT01052324
Locations
🇰🇷

Severance Hospital, Seoul, Korea, Republic of

Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.

First Posted Date
2010-01-13
Last Posted Date
2011-04-14
Lead Sponsor
Basque Health Service
Target Recruit Count
60
Registration Number
NCT01048398
Locations
🇪🇸

Hospital Txagorritxu, Vitoria-Gasteiz, Alava, Spain

Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients

First Posted Date
2010-01-07
Last Posted Date
2015-06-25
Lead Sponsor
Aalborg University Hospital
Target Recruit Count
157
Registration Number
NCT01043952
Locations
🇩🇰

Aalborg Hospital, 4th. dept of Anaesthesiology, Division for Ear Nose and Troath anaesthesia, Aalborg, Nord Jylland, Denmark

Efficacy of Remifentanil Compared to Lidocaine on the Incidence of Coughing During Emergence of Anesthesia

Not Applicable
Completed
Conditions
Cough
Anesthesia
Extubation
Interventions
Drug: Remifentanil
Drug: lidocaine
First Posted Date
2009-12-04
Last Posted Date
2010-07-14
Lead Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Target Recruit Count
93
Registration Number
NCT01026129
Locations
🇨🇦

Centre Hospitalier de l'Université de Montréal-Hôpital Notre-Dame, Montreal, Quebec, Canada

Assessment of the Nociception During Lumbar Surgery

Not Applicable
Completed
Conditions
Lumbar Surgery
Interventions
Drug: remifentanil
First Posted Date
2009-11-18
Last Posted Date
2010-04-07
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
16
Registration Number
NCT01015651
Locations
🇫🇷

University Hospital Grenoble, Grenoble, France

The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)

Phase 4
Conditions
Hyperalgesia
Interventions
Drug: Midazolam
Drug: Remifentanil
First Posted Date
2009-11-18
Last Posted Date
2009-11-18
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT01015482
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

New Options for Preoperative Anesthesia in Intrauterine Needling

Phase 1
Completed
Conditions
Pain
Stress
Interventions
Drug: Remifentanil
Drug: saline
First Posted Date
2009-11-13
Last Posted Date
2009-12-08
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
50
Registration Number
NCT01013558
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers

Phase 4
Conditions
Hyperalgesia
Interventions
Drug: Remifentanil
Drug: Midazolam
First Posted Date
2009-04-22
Last Posted Date
2009-11-18
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT00886106
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

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