Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation

The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers

Phase 4
Conditions
Interventions
First Posted Date
2008-12-19
Last Posted Date
2009-11-18
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT00811837
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

Intravenous Remifentanil Patient-controlled Analgesia (PCA) and Epidural Patient Controlled Epidural Analgesia (PCEA) for Labor Analgesia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-12-03
Last Posted Date
2015-04-21
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
50
Registration Number
NCT00801047
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers

Phase 4
Conditions
Interventions
First Posted Date
2008-11-11
Last Posted Date
2009-05-21
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT00789386
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

Modulation of Remifentanil-induced Postinfusion Hyperalgesia

First Posted Date
2008-11-05
Last Posted Date
2011-07-01
Lead Sponsor
Ullevaal University Hospital
Target Recruit Count
16
Registration Number
NCT00785863
Locations
🇳🇴

Ullevaal University Hospital, Oslo, Norway

Use of Closed-loop Anesthesia in Pediatric Patients

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2008-10-23
Last Posted Date
2016-09-23
Lead Sponsor
Hopital Foch
Target Recruit Count
45
Registration Number
NCT00778505
Locations
🇫🇷

Hôpital Foch, Suresnes, France

🇫🇷

Hôpital Necker Enfants, Paris, France

Influence of Intraoperative Analgesia on the Postoperative Morphine Consumption

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-10-15
Last Posted Date
2016-09-23
Lead Sponsor
Hopital Foch
Target Recruit Count
60
Registration Number
NCT00772616
Locations
🇫🇷

Hopital Foch, Suresnes, France

Requirement of Analgesics After Two Remifentanil Dosing Regimen in Cardiac Surgery.

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-09-23
Last Posted Date
2013-09-12
Lead Sponsor
Kuopio University Hospital
Target Recruit Count
90
Registration Number
NCT00757198
Locations
🇫🇮

Kuopio University hospital, Kuopio, Finland

Intravenous Remifentanil for Labor Analgesia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-07-04
Last Posted Date
2009-09-18
Lead Sponsor
Nanjing Medical University
Target Recruit Count
1000
Registration Number
NCT00710086
Locations
🇨🇳

Nanjing Maternal and Child Health Care Hospital, Nanjing, Jiangsu, China

Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function

First Posted Date
2008-06-27
Last Posted Date
2009-02-10
Lead Sponsor
Medical University Innsbruck
Target Recruit Count
60
Registration Number
NCT00706277
Locations
🇦🇹

TILAK Hospitals, Innsbruck, Austria

Effect of Spinal Ketorolac After Acute Opioid Exposure

First Posted Date
2008-06-06
Last Posted Date
2018-09-07
Lead Sponsor
Wake Forest University
Target Recruit Count
30
Registration Number
NCT00693160
Locations
🇺🇸

Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

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