Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

Effect of Remifentanil on Electroencephalographic BAR Index During Propofol Anaesthesia

Phase 1
Completed
Conditions
Depth of Anaesthesia
Interventions
Drug: remifentanil
First Posted Date
2007-04-03
Last Posted Date
2013-05-30
Lead Sponsor
Melbourne Health
Target Recruit Count
45
Registration Number
NCT00455026
Locations
🇦🇺

Swinburne University, Hawthorn, Victoria, Australia

🇦🇺

Royal Melbourne Hospital, Parkville, Victoria, Australia

Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)

Phase 3
Terminated
Conditions
Analgesia
Interventions
Drug: Propofol
Drug: Remifentanil
First Posted Date
2007-02-19
Last Posted Date
2017-05-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
39
Registration Number
NCT00436345
Locations
🇮🇹

GSK Investigational Site, Palermo, Sicilia, Italy

Neuronal Mechanisms of Sensory Processing During General Anesthesia

Not Applicable
Conditions
General Anesthesia
First Posted Date
2007-02-13
Last Posted Date
2010-07-30
Lead Sponsor
Ludwig-Maximilians - University of Munich
Target Recruit Count
768
Registration Number
NCT00434382
Locations
🇩🇪

Klinik fuer Anaesthesiologie am Universitätsklinikum Schleswig Holstein, Campus Luebeck, Lubeck, Germany

🇩🇪

Klinik fuer Anaesthesiologie der Ludwigs-Maximilians-Universitaet Muenchen, Munich, Germany

🇩🇪

Krankenhaus Friedrichshafen, Friedrichshafen, Germany

and more 1 locations

A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation.

Phase 4
Terminated
Conditions
Analgesia
Sedation
First Posted Date
2007-01-12
Last Posted Date
2018-04-03
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
164
Registration Number
NCT00421720
Locations
🇩🇪

GSK Clinical Trials Call Center, Tubingen, Germany

Rapip Study: Clinical Trial on Remifentanyl for Analgesia and Sedation of Ventilated Neonates and Infants

Phase 3
Completed
Conditions
Mechanical Ventilation
Interventions
Drug: Remifentanyl
Drug: Fentanyl
First Posted Date
2007-01-08
Last Posted Date
2010-06-25
Lead Sponsor
University of Cologne
Target Recruit Count
24
Registration Number
NCT00419601
Locations
🇩🇪

Clinic for Paediatrics, University of Cologne Kerpener Str. 62, Cologne, Germany

Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome

Phase 4
Completed
Conditions
Respiratory Distress Syndrome
First Posted Date
2006-10-23
Last Posted Date
2006-10-23
Lead Sponsor
Federal University of Minas Gerais
Registration Number
NCT00391105

Comparison of Tramadol vs Remifentanyl Patient Controlled Analgesia for Second Trimester Abortions

Not Applicable
Completed
Conditions
Abortion,Induced
First Posted Date
2006-08-08
Last Posted Date
2015-11-24
Lead Sponsor
Rabin Medical Center
Target Recruit Count
40
Registration Number
NCT00361686
Locations
🇮🇱

Rabin Medical Center, Petach Tiqvah, Israel

Dexmedetomidine vs. Remifentanil for Sedation During AFI

Phase 4
Completed
Conditions
Intubation, Endotracheal
First Posted Date
2006-07-06
Last Posted Date
2016-03-23
Lead Sponsor
The University of Texas Health Science Center, Houston
Target Recruit Count
30
Registration Number
NCT00349245
Locations
🇺🇸

Memorial Hermann Hospital, Houston, Texas, United States

The Effects of Dexmedetomidine and Remifentanil on Carotid Patients

First Posted Date
2006-06-12
Last Posted Date
2017-08-11
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
142
Registration Number
NCT00335972
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

Comparison of Monitored Anesthesia Care Using Remifentanil or Fentanyl for Major Dressing Changes in Burns

Phase 4
Terminated
Conditions
Burns
Pain
First Posted Date
2006-05-17
Last Posted Date
2006-10-13
Lead Sponsor
Montreal Burn Centre
Target Recruit Count
40
Registration Number
NCT00326859
Locations
🇨🇦

Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

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