Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
- Associated Therapies
- -
BCD With or Without Doxycycline in Mayo Stage II-III Light Chain Amyloidosis Patients
- Conditions
- Interventions
- First Posted Date
- 2018-01-17
- Last Posted Date
- 2021-02-23
- Lead Sponsor
- Jian Li
- Target Recruit Count
- 140
- Registration Number
- NCT03401372
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, China
Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman.
- First Posted Date
- 2017-11-07
- Last Posted Date
- 2023-07-18
- Lead Sponsor
- Nantes University Hospital
- Target Recruit Count
- 158
- Registration Number
- NCT03334682
- Locations
- 🇫🇷
CH La Rochelle, La Rochelle, France
🇫🇷CH Le Mans, Le Mans, France
🇫🇷Chru Brest, Brest, France
S. Aureus Decolonization in HPN Patients.
- First Posted Date
- 2017-06-01
- Last Posted Date
- 2022-05-31
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 63
- Registration Number
- NCT03173053
- Locations
- 🇩🇰
Rigshospitalet, Copenhagen, Denmark
🇩🇰Aalborg Universitetshospital, Aalborg, Denmark
🇳🇱Radboud UMC, Nijmegen, Gelderland, Netherlands
Effect of Topical Azithromycin on Tear Film Thickness in Patients With Meibomian Gland Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2017-05-22
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 80
- Registration Number
- NCT03162497
- Locations
- 🇦🇹
Gerhard Garhofer, Vienna, Austria
CTCL Directed Therapy
- First Posted Date
- 2017-04-17
- Last Posted Date
- 2019-08-13
- Lead Sponsor
- James J. Peters Veterans Affairs Medical Center
- Target Recruit Count
- 8
- Registration Number
- NCT03116659
- Locations
- 🇺🇸
James J Peters Bronx Veterans Affairs Medical Center, Bronx, New York, United States
Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 56
- Registration Number
- NCT03115177
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-03-10
- Last Posted Date
- 2018-12-24
- Target Recruit Count
- 7
- Registration Number
- NCT03076281
- Locations
- 🇺🇸
Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania, United States
A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in Sri Lanka
- Conditions
- Interventions
- First Posted Date
- 2016-10-10
- Last Posted Date
- 2021-03-17
- Lead Sponsor
- The Task Force for Global Health
- Target Recruit Count
- 219
- Registration Number
- NCT02929134
- Locations
- 🇱🇰
University of Ruhuna, Galle, Southern Province, Sri Lanka
A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India
- Conditions
- Interventions
- First Posted Date
- 2016-10-10
- Last Posted Date
- 2021-06-24
- Lead Sponsor
- The Task Force for Global Health
- Target Recruit Count
- 235
- Registration Number
- NCT02929121
- Locations
- 🇮🇳
Filariasis Research Unit Govt. T. D. Medical College Hospital, Alappuzha, Kerala, India
A 24 Month Study, to Compare the Efficacy of Doxycycline vs. Placebo for Improving Filarial Lymphedema in Mali
- Conditions
- Interventions
- First Posted Date
- 2016-10-07
- Last Posted Date
- 2021-06-24
- Lead Sponsor
- The Task Force for Global Health
- Target Recruit Count
- 220
- Registration Number
- NCT02927496
- Locations
- 🇲🇱
International Centers for Excellence in Research-Mali, Filariasis Res. Unit., Bamako, Mali
Drug Development Updates
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