Doxycycline

Generic Name
Doxycycline
Brand Names
Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
Drug Type
Small Molecule
Chemical Formula
C22H24N2O8
CAS Number
564-25-0
Unique Ingredient Identifier
334895S862
Background

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is...

Indication

Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:

It is also used to treat infections caused by the following gram-negative microorganisms:

Associated Conditions
Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
Associated Therapies
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Low Glycemic Index and Load Diet for the Treatment of Acne

First Posted Date
2018-07-12
Last Posted Date
2018-07-16
Lead Sponsor
Centro Dermatológico Dr. Ladislao de la Pascua
Target Recruit Count
52
Registration Number
NCT03585140

Comparison of Doxycycline and Cefuroxime Axetil in Erythema Migrans

First Posted Date
2018-07-12
Last Posted Date
2018-07-12
Lead Sponsor
University Medical Centre Ljubljana
Target Recruit Count
509
Registration Number
NCT03584919

Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection

First Posted Date
2018-05-22
Last Posted Date
2018-06-04
Lead Sponsor
University Hospital, Bordeaux
Target Recruit Count
460
Registration Number
NCT03532464
Locations
🇫🇷

CeGIDD - Marseille, Marseille, Marignane, France

🇫🇷

Hôpital Hôtel Dieu, Paris, France

🇫🇷

CeGGID - Bordeaux, Bordeaux, France

and more 4 locations

Treatment of Macrolide-resistant Mycoplasma Pneumoniae

First Posted Date
2018-05-21
Last Posted Date
2021-07-28
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
100
Registration Number
NCT03530319
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Pharmacokinetics of Doxycycline in Skin of Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-03-27
Last Posted Date
2018-03-27
Lead Sponsor
Medical University of Vienna
Target Recruit Count
6
Registration Number
NCT03478436
Locations
🇦🇹

Medical University of Vienna, Vienna, Austria

A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy

First Posted Date
2018-03-22
Last Posted Date
2024-07-11
Lead Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia
Target Recruit Count
19
Registration Number
NCT03474458
Locations
🇫🇷

CHU Limoges, Limoges, France

🇩🇪

University Hospital, Heidelberg, Germany

🇬🇷

Alexandra Hospital, Athens, Greece

and more 5 locations

Indwelling Pleural Catheters with or Without Doxycycline in Treating Patients with Malignant Pleural Effusions

First Posted Date
2018-03-14
Last Posted Date
2024-10-01
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
208
Registration Number
NCT03465774
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Efficacy of Doxycycline in the Treatment of Early Stages of Mycosis Fungoides

Phase 3
Conditions
Interventions
First Posted Date
2018-03-06
Last Posted Date
2018-08-23
Lead Sponsor
Cairo University
Target Recruit Count
30
Registration Number
NCT03454945
Locations
🇪🇬

Dermatology departement, Cairo, Egypt

🇪🇬

Dermatology department, Cairo, Egypt

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