Doxycycline
- Generic Name
- Doxycycline
- Brand Names
- Acticlate, Adoxa, Apprilon, Atridox, Doryx, Doxy, Doxycin, Lymepak, Mondoxyne, Monodox, Morgidox, Okebo, Oracea, Periostat, Targadox, Vibramycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 564-25-0
- Unique Ingredient Identifier
- 334895S862
- Background
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.
- Indication
Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria, including:
It is also used to treat infections caused by the following gram-negative microorganisms:
- Associated Conditions
- Acinetobacter Infections, Anthrax, Bacterial Infection caused by Enterobacter aerogenes, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydia Trachomatis Infection, Early Lyme Disease, Granuloma Inguinale, Infection Due to Escherichia Coli, Inhalational Anthrax, Klebsiella Infections, Lymphogranuloma Venereum, Malaria caused by Plasmodium falciparum, Nongonococcal urethritis, Plague caused by Yersinia pestis, Psittacosis, Rectal infection caused by Chlamydia Trachomatis, Relapsing fever caused by Borrelia recurrentis, Respiratory Tract Infection Bacterial, Rickettsial infectious disorders, Severe Acne, Sexually Transmitted Infections (STIs), Shigella Infection, Trachoma inclusion conjunctivitis, Tularemia, Vibrio Cholerae Infection, Acute Intestinal amebiasis, Susceptible Bacterial Infections, Uncomplicated endocervical infection, Uncomplicated urethral infection
Multi-model Image of Doxycycline in TAO
- Conditions
- Thyroid Associated Ophthalmopathy
- Interventions
- First Posted Date
- 2021-11-08
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 20
- Registration Number
- NCT05112211
- Locations
- 🇨🇳
Zhongshan Ophthalmic Center, Guangzhou, Guangdong, China
Lefamulin for M. Genitalium Treatment Failures
- Conditions
- Mycoplasma Genitalium Infection
- Interventions
- First Posted Date
- 2021-11-08
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 12
- Registration Number
- NCT05111002
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Collaborative Urological Prosthetics Investigation Directive Research Group
- Conditions
- Erectile DysfunctionPenile Prosthesis Infection
- Interventions
- First Posted Date
- 2021-10-29
- Last Posted Date
- 2025-03-10
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 800
- Registration Number
- NCT05100654
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Helicobacter Pylori Eradication and Follow-up
- Conditions
- Helicobacter Pylori Infection
- Interventions
- First Posted Date
- 2021-09-30
- Last Posted Date
- 2021-09-30
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 4447
- Registration Number
- NCT05061732
- Locations
- 🇨🇳
Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Tetracycline Versus Doxycycline for HP Rescue Therapy
- Conditions
- Helicobacter Pylori Infection
- Interventions
- First Posted Date
- 2021-08-24
- Last Posted Date
- 2021-08-26
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 242
- Registration Number
- NCT05018923
- Locations
- 🇨🇳
Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Skin Microbiome Profile in Hailey-Hailey Disease
- First Posted Date
- 2021-08-16
- Last Posted Date
- 2021-08-16
- Lead Sponsor
- Gangnam Severance Hospital
- Target Recruit Count
- 18
- Registration Number
- NCT05007223
- Locations
- 🇰🇷
GangnamSeveracne Hospital, Seoul, Korea, Republic of
Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI
- Conditions
- Cancer, Treatment-RelatedAcneiform Eruptions
- Interventions
- First Posted Date
- 2021-04-29
- Last Posted Date
- 2021-09-08
- Lead Sponsor
- Lady Davis Institute
- Target Recruit Count
- 98
- Registration Number
- NCT04864717
- Locations
- 🇨🇦
Jewish General Hospital, Montreal, Quebec, Canada
Combo-PEP: Multipurpose Prevention of Post-Exposure Prophylaxis Regimens
- First Posted Date
- 2021-04-27
- Last Posted Date
- 2023-05-23
- Lead Sponsor
- Emory University
- Target Recruit Count
- 20
- Registration Number
- NCT04860505
- Locations
- 🇺🇸
Hope Clinic, Atlanta, Georgia, United States
Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease Risk
- First Posted Date
- 2021-04-15
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Mario Negri Institute for Pharmacological Research
- Target Recruit Count
- 29
- Registration Number
- NCT04846335
Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY)
- First Posted Date
- 2021-04-09
- Last Posted Date
- 2024-12-30
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 200
- Registration Number
- NCT04838717
- Locations
- 🇫🇷
CHRU Jean Minjoz, Besancon, France
🇫🇷Hôpital Henri Mondor, Créteil, France
🇫🇷Hôpital de la Croix Rousse, Lyon, France
Drug Development Updates
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