Hydroxyethyl Starch
- Generic Name
- Hydroxyethyl Starch
- Brand Names
- Hespan, Hextend, Volulyte, Voluven
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9005-27-0
- Unique Ingredient Identifier
- 875Y4127EA
- Background
Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
- Indication
An intravenous solution of hydroxyethyl starch is used to prevent shock following severe blood loss caused by trauma, surgery, or other issues.
- Associated Conditions
- Hypovolaemia
- Associated Therapies
- Granulocyte yield increase
Stroke Volume Optimisation in Patients With Hip Fracture
- Conditions
- Hip Fractures
- Interventions
- Drug: VOLUVEN and others soluteProcedure: hemodynamic optimisation guided using esophageal Doppler
- First Posted Date
- 2007-03-07
- Last Posted Date
- 2011-10-07
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 215
- Registration Number
- NCT00444262
- Locations
- 🇫🇷
Centre Hospitalier Universitaire de La Cote de Nacre, Caen, Calvados, France
🇫🇷Centre Hospitalier Universitaire de Poitiers, Poitiers, Vienne, France
🇫🇷Hopital La Pitie Salpetriere, Paris, France
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
- Conditions
- Angina PectorisUnstable AnginaMyocardial Infarction
- Interventions
- Procedure: Percutaneous Coronary RevascularizationDrug: VoluvenDrug: Hemoglobin-Based Oxygen Carrier-201 (HBOC-201)
- First Posted Date
- 2006-04-25
- Last Posted Date
- 2008-05-16
- Lead Sponsor
- Biopure Corporation
- Target Recruit Count
- 45
- Registration Number
- NCT00317512
- Locations
- 🇧🇪
Site # 6 Antwerpen, Antwerpen, Belgium
🇩🇪Site # 2 Herzzentrum, Leipzig, Germany
🇧🇪Site # 5 Onze Lieve Vrouw Ziekenhuis (OLVZ), Aalst, Belgium
Hetastarch and Bleeding Complications After Off-Pump Coronary Bypass Surgery
- Conditions
- Postoperative Hemorrhage
- First Posted Date
- 2006-03-27
- Last Posted Date
- 2006-05-22
- Lead Sponsor
- Kaiser Permanente
- Target Recruit Count
- 330
- Registration Number
- NCT00307138
- Locations
- 🇺🇸
Summit Medical Center, Oakland, California, United States
Drug Development Updates
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