Metoprolol
- Generic Name
- Metoprolol
- Brand Names
- Kapspargo, Lopressor, Lopressor Hct, Toprol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25NO3
- CAS Number
- 51384-51-1
- Unique Ingredient Identifier
- GEB06NHM23
- Background
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferre...
- Indication
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.
...
- Associated Conditions
- Angina Pectoris, Atrial Fibrillation, Hypertension, Migraine, Myocardial Infarction, Supraventricular Tachycardia (SVT), Thyroid Crisis, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents
- Conditions
- First Posted Date
- 2007-05-21
- Last Posted Date
- 2007-05-21
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 28
- Registration Number
- NCT00475462
Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
- Conditions
- Interventions
- First Posted Date
- 2006-11-22
- Last Posted Date
- 2017-05-25
- Lead Sponsor
- David Haines, MD
- Target Recruit Count
- 7
- Registration Number
- NCT00401882
- Locations
- 🇺🇸
William Beaumont Hospital, Royal Oak, Michigan, United States
A Comparison of the Effect of Carvedilol and Metoprolol on Airways Tone in Patients With Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2006-10-06
- Last Posted Date
- 2015-06-24
- Lead Sponsor
- The Alfred
- Registration Number
- NCT00384566
- Locations
- 🇦🇺
Alfred Hospital, Melbourne, Victoria, Australia
RATe Control in Atrial Fibrillation
- Conditions
- Interventions
- First Posted Date
- 2006-04-12
- Last Posted Date
- 2014-05-13
- Lead Sponsor
- Asker & Baerum Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT00313157
- Locations
- 🇳🇴
Vestre Viken Hospital Trust, Baerum Hospital, Rud, Akershus, Norway
Use of Beta Blockers in Elderly Trauma Patients
- Conditions
- First Posted Date
- 2006-03-14
- Last Posted Date
- 2007-05-10
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 148
- Registration Number
- NCT00302692
- Locations
- 🇺🇸
Parkland Memorial Hospital, Dallas, Texas, United States
Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- First Posted Date
- 2006-02-08
- Last Posted Date
- 2006-02-20
- Lead Sponsor
- Martini Hospital Groningen
- Target Recruit Count
- 45
- Registration Number
- NCT00288548
- Locations
- 🇳🇱
Martini Hospital, Groningen, Netherlands
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
- Conditions
- First Posted Date
- 2005-09-26
- Last Posted Date
- 2008-06-26
- Lead Sponsor
- The George Institute
- Target Recruit Count
- 404
- Registration Number
- NCT00226096
- Locations
- 🇦🇺
Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
🇦🇺Royal Adelaide Hospital, Adelaide, South Australia, Australia
🇦🇺Royal Melbourne Hospital, Melbourne, Victoria, Australia
Treatment of Supine Hypertension in Autonomic Failure
- Conditions
- Interventions
- Drug: PlaceboDrug: ClonidineDrug: Nitroglycerin transdermalDrug: Dipyridamole/ Aspirin (Aggrenox)Drug: Desmopressin (DDAVP)Drug: SildenafilDrug: NifedipineDrug: HydralazineDrug: HydrochlorothiazideDrug: BosentanDrug: DiltiazemDrug: EplerenoneDrug: guanfacineDietary Supplement: L-arginineDrug: captoprilDrug: carbidopaDrug: losartanDrug: metoprolol tartrateDrug: nebivolol hydrochlorideDrug: prazosin hydrochlorideDrug: tamsulosin hydrochlorideOther: Head-up tilt.Drug: aliskirenOther: Local heat stress
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2017-10-13
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 152
- Registration Number
- NCT00223717
- Locations
- 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States
Effect of Losartan on Retinal Endothelial Function in Patients With Essential Hypertension
- First Posted Date
- 2005-09-09
- Last Posted Date
- 2012-07-06
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Registration Number
- NCT00152633
- Locations
- 🇩🇪
CRC, Med. Klinik 4, University of Erlangen-Nürnberg, Erlangen, Germany
Vascular Effects of Carvedilol Versus Metoprolol in Hypertensive Patients With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2005-07-25
- Last Posted Date
- 2014-11-18
- Lead Sponsor
- St. Paul Heart Clinic
- Target Recruit Count
- 36
- Registration Number
- NCT00123604
- Locations
- 🇺🇸
St. Paul Heart Clinic, St. Paul, Minnesota, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.